Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3782395 | 0.90 | CYP2C9 (0.45) | CYP2C9ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3782444 | 0.83 | CYP2C9 (0.46) | CYP2C9ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3295932 | 0.74 | CYP2C9 (0.47) | CYP2C9ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL5907704 | 0.74 | CYP2C9 (0.47) | CYP2C9ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3791370 | 0.73 | CYP2C9 (0.41) | CYP2C9ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3787971 | 0.73 | MAPT (0.49) | CYP2C9ALDH1A1HPGDAKR1C3TDP1 | |
| SCHEMBL4914016 | 0.72 | TRPA1 (0.31) | CYP2C9 | |
| SCHEMBL3624272 | 0.72 | TDP1 (0.48) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL197322 | 0.72 | GRIK1 (0.53) | CYP2C9ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL197321 | 0.72 | GRIK1 (0.53) | CYP2C9ALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100183540-A1 | BRANCHED POLYMER AND ANTIFOULING COATING COMPOSITION COMPRISING THE POLYMER | JOTUN A/S (NO) | 2010-07-22 | — | — | US | disclosed |