SCHEMBL3782444

SCHEMBL3782444

CC(=C[Si](C)(C)Cc1ccccc1)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.46
AKR1C3 P42330 1/20 0.44
ALDH1A1 P00352 3/20 0.43
MAPT P10636 1/20 0.41
CTRB1 P17538 4/20 0.39
TBXAS1 P24557 3/20 0.39
LMNA P02545 1/20 0.38
RXRA P19793 1/20 0.38
RXRB P28702 1/20 0.38
NR4A2 P43354 1/20 0.38
RXRG P48443 1/20 0.38
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
AKR1B1 P15121 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5907704 0.84 CYP2C9 (0.47) CYP2C9AKR1C3ALDH1A1MAPTCTRB1
SCHEMBL3295932 0.84 CYP2C9 (0.47) CYP2C9AKR1C3ALDH1A1MAPTCTRB1
SCHEMBL3783448 0.83 CYP2C9 (0.47) CYP2C9AKR1C3ALDH1A1MAPTNPC1
SCHEMBL3782395 0.80 CYP2C9 (0.45) CYP2C9ALDH1A1MAPTNPC1RAB9A
SCHEMBL18270286 0.74 L3MBTL1 (0.41) CYP2C9ALDH1A1CTRB1CES2CES1
SCHEMBL3293184 0.72 MAPT (0.49) CYP2C9AKR1C3ALDH1A1MAPTRXRA
SCHEMBL3787971 0.72 MAPT (0.49) CYP2C9AKR1C3ALDH1A1MAPTRXRA
SCHEMBL3781076 0.71 CYP2C9 (0.40) CYP2C9AKR1C3ALDH1A1MAPTTBXAS1
SCHEMBL3294518 0.70 TRPA1 (0.33) AKR1C3
SCHEMBL3297070 0.69 AKR1C3 (0.50) CYP2C9AKR1C3ALDH1A1MAPTRXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2935288-A1 SILYL ESTER COPOLYMER Jotun A/S (NO) 2015-10-28 EP disclosed
WO-2014096102-A1 SILYL ESTER COPOLYMER JOTUN A/S (NO) 2014-06-26 WO disclosed
US-20100183540-A1 BRANCHED POLYMER AND ANTIFOULING COATING COMPOSITION COMPRISING THE POLYMER JOTUN A/S (NO) 2010-07-22 US disclosed