SCHEMBL3783555

SCHEMBL3783555

CCCCCCCCC(CCCCCC)COC(=O)OC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ZDHHC7 Q9NXF8 1/20 0.55
PRSS1 P07477 1/20 0.50
PRSS2 P07478 1/20 0.50
PRSS3 P35030 1/20 0.50
TSHR P16473 2/20 0.47
CYP3A4 P08684 2/20 0.47
ATM Q13315 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
LMNA P02545 2/20 0.47
PLA2G2A P14555 1/20 0.44
CA2 P00918 2/20 0.44
CA1 P00915 1/20 0.44
ABCB1 P08183 1/20 0.43
PLA2G2C Q5R387 1/20 0.42
GPR84 Q9NQS5 3/20 0.42
FFAR1 O14842 1/20 0.42
USP2 O75604 1/20 0.42
ALDH1A1 P00352 1/20 0.41
MAPT P10636 2/20 0.41
EPHX1 P07099 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18856337 1.00 ZDHHC7 (0.55) ZDHHC7PRSS1PRSS2PRSS3TSHR
SCHEMBL3781584 0.98 ZDHHC7 (0.53) ZDHHC7PRSS1PRSS2PRSS3TSHR
SCHEMBL29240282 0.92 PRSS1 (0.53) ZDHHC7PRSS1PRSS2PRSS3TSHR
SCHEMBL2990536 0.92 PRSS1 (0.53) ZDHHC7PRSS1PRSS2PRSS3TSHR
SCHEMBL27008512 0.92 PRSS1 (0.53) ZDHHC7PRSS1PRSS2PRSS3TSHR
SCHEMBL26633470 0.92 PRSS1 (0.53) ZDHHC7PRSS1PRSS2PRSS3TSHR
SCHEMBL8508059 0.90 TSHR (0.53) ZDHHC7PRSS1PRSS2PRSS3TSHR
SCHEMBL12646272 0.87 PRSS1 (0.49) ZDHHC7PRSS1PRSS2PRSS3TSHR
SCHEMBL21259198 0.87 PRSS1 (0.49) ZDHHC7PRSS1PRSS2PRSS3TSHR
SCHEMBL3781285 0.86 TSHR (0.49) ZDHHC7PRSS1PRSS2PRSS3TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10544086-B2 Dialkyl carbonates of branched alcohols and their use COGNIS IP MANAGEMENT GMBH (DE) 2020-01-28 US disclosed
US-20170260123-A1 DIALKYL CARBONATES OF BRANCHED ALCOHOLS AND THEIR USE COGNIS IP MANAGEMENT GMBH (DE) 2017-09-14 US disclosed
US-8039532-B2 Heterocyclic compound, ultraviolet absorbent and composition containing the same FUJIFILM CORPORATION (JP) 2011-10-18 US disclosed
US-20100331565-A1 Dialkyl Carbonates of Branched Alcohols and their Use COGNIS IP MANAGEMENT GMBH (DE) 2010-12-30 US disclosed
US-20100210762-A1 HETEROCYCLIC COMPOUND, ULTRAVIOLET ABSORBENT AND COMPOSITION CONTAINING THE SAME FUJIFILM CORPORATION (JP) 2010-08-19 US disclosed
US-20100130638-A1 ULTRAVIOLET ABSORBENT COMPOSITION FUJIFILM CORPORATION (JP) 2010-05-27 US disclosed
US-20100025642-A1 ULTRAVIOLET ABSORBENT COMPOSITION FUJIFILM CORPORATION (JP) 2010-02-04 US disclosed
EP-2094641-A1 DIALKYL CARBONATES OF BRANCHED ALCOHOLS AND THEIR USE Cognis IP Management GmbH (DE) 2009-09-02 EP disclosed
WO-2008067946-A1 DIALKYL CARBONATES OF BRANCHED ALCOHOLS AND THEIR USE COGNIS IP MANAGEMENT GMBH (DE) 2008-06-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100210762-A1 HETEROCYCLIC COMPOUND, ULTRAVIOLET ABSORBENT AND COMPOSITION CONTAINING THE SAME F12, F2, CYP24A1 ZDHHC7 4275/4885PRSS1 1034/4885PRSS2 667/4885
US-10544086-B2 Dialkyl carbonates of branched alcohols and their use ADH1C, ADH1A, GALK1 ZDHHC7 2946/4885PRSS1 4033/4885PRSS2 3983/4885
US-20170260123-A1 DIALKYL CARBONATES OF BRANCHED ALCOHOLS AND THEIR USE ADH1C, ADH1A, GALK1 ZDHHC7 2946/4885PRSS1 4033/4885PRSS2 3983/4885
US-20100331565-A1 Dialkyl Carbonates of Branched Alcohols and their Use GALK1, BCKDK, ADH1C ZDHHC7 2262/4885PRSS1 4287/4885PRSS2 4029/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.