Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528353 | 0.88 | CHRM2 (0.35) | CHRM2CHRM4CHRM5ADRA2ACHRM1 | |
| SCHEMBL242711 | 0.84 | CHRM2 (0.35) | CHRM2CHRM4CHRM5ADRA2ACHRM1 | |
| SCHEMBL3783903 | 0.81 | HTR1A (0.40) | LMNAADRA1DKDM4EHSD17B10HPGD | |
| SCHEMBL242002 | 0.72 | NR4A2 (0.40) | CHRM2CHRM4CHRM5ADRA2ACHRM1 | |
| SCHEMBL4986900 | 0.70 | HTR1A (0.49) | ADRA1D | |
| SCHEMBL527640 | 0.70 | HTR1A (0.39) | LMNAADRA1DKDM4EMAPTALDH1A1 | |
| SCHEMBL13993581 | 0.67 | PDE5A (0.44) | LMNAADRA1DKDM4EMAPTHSD17B10 | |
| SCHEMBL7986573 | 0.65 | MAPT (0.55) | CHRM2CHRM4CHRM5ADRA2ACHRM1 | |
| SCHEMBL241926 | 0.65 | HTR1A (0.40) | LMNAADRA1DKDM4EMAPTALDH1A1 | |
| SCHEMBL240627 | 0.64 | PDE5A (0.35) | CHRM2CHRM4CHRM5ADRA2ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010088544-A1 | METHODS TO TREAT CANCER | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2010-08-05 | — | — | WO | disclosed |