Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV6 | Q9H1D0 | 3/20 | 0.64 |
| ▸ | L3MBTL3 | Q96JM7 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | DRD4 | P21917 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MBTD1 | Q05BQ5 | 2/20 | 0.53 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3788371 | 0.99 | TRPV6 (0.63) | TRPV6L3MBTL3L3MBTL1KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL3710266 | 0.93 | MAPT (0.60) | TRPV6L3MBTL3L3MBTL1KDM4EMEN1 | |
| SCHEMBL3711524 | 0.90 | DRD4 (0.70) | TRPV6L3MBTL3L3MBTL1ALDH1A1DRD4 | |
| Hydrochloric Acid SCHEMBL3793856 | 0.89 | DRD4 (0.68) | TRPV6L3MBTL3L3MBTL1ALDH1A1DRD4 | |
| SCHEMBL12261943 | 0.85 | DRD4 (0.77) | DRD4 | |
| SCHEMBL3712719 | 0.84 | MAPT (0.74) | L3MBTL3L3MBTL1ALDH1A1KMT2ADRD4 | |
| SCHEMBL3716319 | 0.84 | L3MBTL1 (0.67) | L3MBTL3L3MBTL1KDM4EALDH1A1DRD4 | |
| Hydrochloric Acid SCHEMBL3706847 | 0.83 | MAPT (0.72) | L3MBTL3L3MBTL1ALDH1A1KMT2ADRD4 | |
| Hydrochloric Acid SCHEMBL3716101 | 0.83 | L3MBTL1 (0.65) | L3MBTL3L3MBTL1KDM4EALDH1A1DRD4 | |
| SCHEMBL3709310 | 0.82 | RECQL (0.70) | TRPV6KDM4EALDH1A1DRD4RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | disclosed |
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | disclosed |