Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.67 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.67 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.67 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.61 |
| ▸ | DRD2 | P14416 | 3/20 | 0.57 |
| ▸ | DRD3 | P35462 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | DRD4 | P21917 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3716101 | 0.98 | L3MBTL1 (0.65) | L3MBTL1L3MBTL3MBTD1GRIN2BDRD2 | |
| SCHEMBL3784411 | 0.84 | TRPV6 (0.64) | L3MBTL1L3MBTL3MBTD1MAPTALDH1A1 | |
| SCHEMBL14161697 | 0.84 | GRIN2B (0.76) | L3MBTL1L3MBTL3MBTD1GRIN2BDRD2 | |
| SCHEMBL18590696 | 0.84 | CHKA (0.67) | MAPTGAADRD4KDM4EHRH3 | |
| SCHEMBL18867080 | 0.83 | L3MBTL3 (0.53) | L3MBTL1L3MBTL3MBTD1GRIN2BALDH1A1 | |
| Hydrochloric Acid SCHEMBL3710266 | 0.83 | MAPT (0.60) | L3MBTL1L3MBTL3DRD2DRD3MAPT | |
| Hydrochloric Acid SCHEMBL3788371 | 0.83 | TRPV6 (0.63) | L3MBTL1L3MBTL3MBTD1MAPTALDH1A1 | |
| SCHEMBL28784973 | 0.83 | HRH3 (0.48) | L3MBTL1L3MBTL3MBTD1GRIN2BDRD2 | |
| SCHEMBL3713534 | 0.82 | CYP2D6 (0.47) | L3MBTL1L3MBTL3MBTD1GRIN2BDRD2 | |
| SCHEMBL3640868 | 0.81 | CHKA (0.50) | L3MBTL1L3MBTL3MBTD1GRIN2BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | claimed |
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | disclosed |