SCHEMBL335309

SCHEMBL335309

COc1ccc(C[C@H](NC(=O)OC(C)(C)C)C(=O)O)cc1

nearest known ligand 0.67

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 1/20 0.67
ITGA2B P08514 1/20 0.67
PPARG P37231 1/20 0.66
PPARA Q07869 1/20 0.66
ACE P12821 1/20 0.61
ITGA4 P13612 2/20 0.58
ITGB7 P26010 2/20 0.58
PTPN1 P18031 3/20 0.57
FPR2 P25090 1/20 0.56
KMT2A Q03164 1/20 0.56
LDHA P00338 1/20 0.55
CTSS P25774 6/20 0.55
CTSK P43235 5/20 0.55
CTSL P07711 1/20 0.54
CTSB P07858 1/20 0.54
CA2 P00918 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL335310 1.00 ITGB3 (0.67) ITGB3ITGA2BPPARGPPARAACE
SCHEMBL1308867 1.00 ITGB3 (0.67) ITGB3ITGA2BPPARGPPARAACE
SCHEMBL3728960 0.96 ITGB3 (0.64) ITGB3ITGA2BPPARGPPARAACE
SCHEMBL3728957 0.96 ITGB3 (0.64) ITGB3ITGA2BPPARGPPARAACE
SCHEMBL8091309 0.90 ITGB3 (0.57) ITGB3ITGA2BPPARGPPARAACE
SCHEMBL16124030 0.90 ITGB3 (0.57) ITGB3ITGA2BPPARGPPARAACE
SCHEMBL16228288 0.90 ITGB3 (0.57) ITGB3ITGA2BPPARGPPARAACE
SCHEMBL16228287 0.90 ITGB3 (0.57) ITGB3ITGA2BPPARGPPARAACE
SCHEMBL12062761 0.90 ITGB3 (0.57) ITGB3ITGA2BPPARGPPARAACE
SCHEMBL16228734 0.90 ITGB3 (0.57) ITGB3ITGA2BPPARGPPARAACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119528812-B Double amino acid-genipin derivative and preparation method and application thereof 广东工业大学 2025-06-03 CN claimed
CN-119528812-A Double amino acid-genipin derivative and preparation method and application thereof 广东工业大学 2025-02-28 CN claimed
CN-112010945-B Preparation method of carbetocin impurity Gly9-OH 成都诺和晟泰生物科技有限公司 2022-09-16 CN claimed
CN-112142825-B Method for synthesizing carbetocin in fragment mode 山东辰龙药业有限公司 2022-03-11 CN claimed
US-5767158-A FOR BLEACHING SKIN SHISEIDO CO., LTD. (JP) 1998-06-16 US claimed
EP-4727552-A2 PASSIVE PERMEABLE PCSK9 ANTAGONIST COMPOUNDS Merck Sharp & Dohme LLC (US) 2026-04-22 EP disclosed
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PEPTIDREAM INC (JP) 2026-01-15 US disclosed
US-20250325508-A1 MODULATORS OF PROTEASOME DYNAMICS AND/OR FUNCTION, COMPOSITIONS, METHODS, AND THERAPEUTIC USES THEREOF TECHNION RES & DEV FOUNDATION (IL) 2025-10-23 US disclosed
US-20250243196-A1 CITRON KINASE INHIBITORS THE CLEVELAND CLINIC FOUNDATION 2025-07-31 US disclosed
CN-119528812-B Double amino acid-genipin derivative and preparation method and application thereof 广东工业大学 2025-06-03 CN disclosed
WO-2025090774-A1 CHEMOTHERAPEUTIC COMPOUNDS AND METHODS OF USE SEAGEN INC. (US) 2025-05-01 WO disclosed
EP-4534524-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PeptiDream Inc. (JP) 2025-04-09 EP disclosed
EP-0403828-A1 Renin-inhibiting peptides, their preparation and their use in medicaments BAYER AG (DE) 1990-12-27 EP disclosed
EP-0401963-A1 Phosphonopeptides with collagenase inhibiting activity Beecham Group p.l.c. (GB) 1990-12-12 EP disclosed
EP-0396065-A1 Novel amino acid derivatives possessing renin-inhibitory activities Japan Tobacco Inc. (JP) 1990-11-07 EP disclosed
WO-1990002137-A1 RENIN INHIBITORY PEPTIDES CONTAINING SULEPTANIC ACID OR DERIVATIVES THEREOF THE UPJOHN COMPANY (US) 1990-03-08 WO disclosed
EP-0312157-A2 Tetrapeptide renin inhibitors having a novel c-terminal amino acid MERCK & CO. INC. (US) 1989-04-19 EP disclosed
EP-0071926-B1 NEW RIBOFURANURONIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1986-10-08 EP disclosed
US-4508645-A CYCLIC OLIGOPEPTIDE CONTAINING PENICILLAMINE RESIDE CESKOSLOVENSKA AKADEMIE VED (CS) 1985-04-02 US disclosed
US-4479942-A Tetrahydrofurnancarboxylic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-10-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250325508-A1 MODULATORS OF PROTEASOME DYNAMICS AND/OR FUNCTION, COMPOSITIONS, METHODS, AND THERAPEUTIC USES THEREOF PSMC1, PSME3, PSMA6 ITGB3 3677/4885ITGA2B 3843/4885PPARG 3376/4885
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF NSUN3, BCAT1, SLC43A1 ITGB3 2864/4885ITGA2B 3805/4885PPARG 3131/4885
US-20250243196-A1 CITRON KINASE INHIBITORS CHEK2, CILK1, DCK ITGB3 3226/4885ITGA2B 3237/4885PPARG 3094/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.