Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 12/20 | 0.71 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3786175 | 0.91 | HDAC2 (0.62) | HDAC2HDAC1HDAC3ALDH1A1GAA | |
| SCHEMBL3791875 | 0.90 | HDAC2 (0.58) | HDAC2HDAC1HDAC3ALDH1A1GAA | |
| SCHEMBL3790648 | 0.90 | HDAC2 (0.57) | HDAC2HDAC1HDAC3ALDH1A1GAA | |
| SCHEMBL3791270 | 0.88 | HDAC2 (0.58) | HDAC2HDAC1HDAC3ALDH1A1GAA | |
| SCHEMBL12933378 | 0.85 | HDAC2 (0.93) | HDAC2HDAC1HDAC3HDAC4HDAC7 | |
| Dimethylamine SCHEMBL1067124 | 0.82 | HDAC2 (0.88) | HDAC2HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL3790195 | 0.81 | HDAC2 (0.49) | HDAC2HDAC1HDAC3ALDH1A1GAA | |
| SCHEMBL3782181 | 0.81 | ALDH1A1 (0.57) | HDAC2HDAC1HDAC3ALDH1A1GAA | |
| SCHEMBL3785129 | 0.80 | ALDH1A1 (0.47) | HDAC2HDAC1HDAC3ALDH1A1GAA | |
| SCHEMBL12933399 | 0.79 | HDAC2 (0.87) | HDAC2HDAC1HDAC3ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | HDAC2 549/4885HDAC1 1686/4885HDAC3 2675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.