SCHEMBL3784976

SCHEMBL3784976

Nc1cccc(-c2cc(N)cc(OCc3ccccc3)c2)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 5/20 0.71
MAOA P21397 2/20 0.53
GAA P10253 1/20 0.53
MAPT P10636 1/20 0.53
RAB9A P51151 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
APP P05067 1/20 0.53
MRGPRX4 Q96LA9 1/20 0.47
GSTP1 P09211 2/20 0.46
FFAR4 Q5NUL3 1/20 0.44
GRM5 P41594 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
ALOX5 P09917 1/20 0.44
AGXT P21549 1/20 0.44
NR4A2 P43354 1/20 0.43
PIK3CD O00329 1/20 0.43
PIK3CA P42336 1/20 0.43
PIK3CB P42338 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3790348 0.92 MAOB (0.62) MAOBMAOAGAAMAPTRAB9A
SCHEMBL3787907 0.90 MAOB (0.81) MAOBMAOAGAAMAPTRAB9A
SCHEMBL3781103 0.86 MAOB (0.64) MAOBMAOAGAAMAPTRAB9A
SCHEMBL3791194 0.86 MAOB (0.68) MAOBMAOAGAAMAPTRAB9A
3-(Benzyloxy)Aniline SCHEMBL29428912 0.83 MAOB (1.00) MAOBMAOAGAAMAPTRAB9A
3-(Benzyloxy)Aniline SCHEMBL291445 0.83 MAOB (1.00) MAOBMAOAGAAMAPTRAB9A
SCHEMBL9170360 0.83 MAOB (0.72) MAOBMAOAGAAMAPTRAB9A
3-(Benzyloxy)Aniline SCHEMBL11263814 0.82 MAOB (0.96) MAOBMAOAGAAMAPTRAB9A
Hydrochloric Acid SCHEMBL3275739 0.81 MAOB (0.70) MAOBMAOAGAAMAPTRAB9A
SCHEMBL2869923 0.81 MAOB (0.81) MAOBMAOAGAAMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100087680-A1 METHOD FOR PRODUCING BIARYL COMPOUND SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2010-04-08 US disclosed
EP-1914221-A1 PROCESS FOR PRODUCING BIARYL COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-04-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100087680-A1 METHOD FOR PRODUCING BIARYL COMPOUND NISCH, BLVRB, BBOX1 MAOB 101/4885MAOA 348/4885GAA 1755/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.