SCHEMBL3785446

SCHEMBL3785446

Nc1c(F)cccc1-c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
HSD17B10 Q99714 2/20 0.50
MAPT P10636 2/20 0.42
DPP4 P27487 2/20 0.40
ADORA2A P29274 2/20 0.40
MAP4K4 O95819 1/20 0.40
CSF1R P07333 1/20 0.40
FGFR1 P11362 1/20 0.40
PDGFRA P16234 1/20 0.40
LTK P29376 1/20 0.40
KDR P35968 1/20 0.40
MAPK8 P45983 1/20 0.40
CSNK1A1 P48729 1/20 0.40
LIMK1 P53667 1/20 0.40
CDK5 Q00535 1/20 0.40
ACVR1 Q04771 1/20 0.40
TNK2 Q07912 1/20 0.40
AURKB Q96GD4 1/20 0.40
CLK4 Q9HAZ1 1/20 0.40
DYRK1B Q9Y463 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29634223 1.00 ALDH1A1 (0.50) ALDH1A1HSD17B10MAPTDPP4ADORA2A
Hydrochloric Acid SCHEMBL9536077 0.98 ALDH1A1 (0.48) ALDH1A1HSD17B10MAPTDPP4ADORA2A
SCHEMBL3787382 0.84 TAAR1 (0.45) ALDH1A1HSD17B10MAPTMAP4K4CSF1R
SCHEMBL1822460 0.83 ALDH1A1 (0.62) ALDH1A1HSD17B10MAPTDPP4MAP4K4
SCHEMBL29048556 0.82 HSD17B10 (0.44) ALDH1A1HSD17B10MAPTDPP4ADORA1
SCHEMBL15051995 0.81 ALDH1A1 (0.45) ALDH1A1MAPTADORA2AMAP4K4ADORA1
SCHEMBL3780887 0.81 MAP4K4 (0.50) ALDH1A1MAPTMAP4K4HPGDMEN1
Hydrochloric Acid SCHEMBL27842035 0.80 ALDH1A1 (0.59) ALDH1A1HSD17B10MAPTDPP4MAP4K4
Methane SCHEMBL15255218 0.80 HSD17B10 (0.43) ALDH1A1HSD17B10MAPTDPP4ADORA2A
SCHEMBL28039705 0.79 NCOA1 (0.53) ALDH1A1HSD17B10MAPK1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122079805-A Preparation method and application of trifluoro-methoxy-amide-containing bridged aromatic amine compound 2026-05-26 CN claimed
CN-109942433-A A kind of chemical synthesis process of 3 ', 4 ', 5 '-three fluoro- 2- aminobphenyls 浙江工业大学 2019-06-28 CN claimed
CN-107628956-A The method of one kind synthesis aminobphenyl of 3,4 difluoro 2 ' 江西天宇化工有限公司 2018-01-26 CN claimed
CN-122079805-A Preparation method and application of trifluoro-methoxy-amide-containing bridged aromatic amine compound 2026-05-26 CN disclosed
CN-118488991-A Resin composition, molded article and film 株式会社钟化 2024-08-13 CN disclosed
CN-116867846-A Polyimide film, method for producing the same, hard coat film, and image display device 株式会社钟化 2023-10-10 CN disclosed
CN-116419848-A Hard coat film, method for producing same, and image display device 株式会社钟化 2023-07-11 CN disclosed
CN-112079743-B Diamine, polyimide and polyimide film 浙江中科玖源新材料有限公司 2023-06-27 CN disclosed
EP-3266790-B1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND SAMSUNG ELECTRONICS CO LTD (KR) 2019-11-06 EP disclosed
CN-109942433-A A kind of chemical synthesis process of 3 ', 4 ', 5 '-three fluoro- 2- aminobphenyls 浙江工业大学 2019-06-28 CN disclosed
CN-109942433-A A kind of chemical synthesis process of 3 ', 4 ', 5 '-three fluoro- 2- aminobphenyls 浙江工业大学 2019-06-28 CN disclosed
US-20100105658-A1 AZA-BRIDGED-RING COMPOUND ASTELLAS PHARMA INC. (JP) 2010-04-29 US disclosed
US-20100105658-A1 AZA-BRIDGED-RING COMPOUND ASTELLAS PHARMA INC. (JP) 2010-04-29 US disclosed
US-20100087680-A1 METHOD FOR PRODUCING BIARYL COMPOUND SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2010-04-08 US disclosed
EP-2119716-A1 AZA-BRIDGED-RING COMPOUND Astellas Pharma Inc. (JP) 2009-11-18 EP disclosed
EP-1914221-A1 PROCESS FOR PRODUCING BIARYL COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-04-23 EP disclosed
EP-1856024-A1 METHOD FOR PRODUCING SUBSTITUTED BIPHENYLS BASF AKTIENGESELLSCHAFT (DE) 2007-11-21 EP disclosed
CN-101065369-A Biphenylthiazolecarboxamides BAYER CROPSCIENCE AG (DE) 2007-10-31 CN disclosed
WO-2006092429-A1 METHOD FOR PRODUCING SUBSTITUTED BIPHENYLS BASF AKTIENGESELLSCAHFT (DE) 2006-09-08 WO disclosed
EP-0536151-A1 ORTHOSUBSTITUTED BIPHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM. BOOTS CO PLC (GB) 1993-04-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100087680-A1 METHOD FOR PRODUCING BIARYL COMPOUND NISCH, BLVRB, BBOX1 ALDH1A1 4339/4885HSD17B10 1100/4885MAPT 3312/4885
US-20100105658-A1 AZA-BRIDGED-RING COMPOUND CHRM3, CHRM1, CHRM2 ALDH1A1 2006/4885HSD17B10 3014/4885MAPT 4405/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.