Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | TNF | P01375 | 1/20 | 0.58 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.58 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.50 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.50 |
| ▸ | NAMPT | P43490 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3793530 | 0.91 | PTPN11 (0.58) | RAB9AKMT2AMEN1NPC1GRIN2D | |
| SCHEMBL3796116 | 0.85 | MAPT (0.59) | RAB9AKMT2AMEN1TNFNOD2 | |
| SCHEMBL3788726 | 0.83 | GRIN2D (0.54) | RAB9AKMT2AMEN1NPC1GRIN2D | |
| SCHEMBL13203909 | 0.83 | GRIN2D (0.61) | RAB9AKMT2AMEN1NPC1GRIN2D | |
| SCHEMBL3794388 | 0.82 | KDM4E (0.60) | RAB9AKMT2ANPC1GRIN2DGRIN3B | |
| SCHEMBL3783683 | 0.81 | GRIN2D (0.55) | RAB9AKMT2AMEN1NPC1GRIN2D | |
| SCHEMBL3063610 | 0.81 | ALDH1A1 (0.60) | RAB9AKMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3058918 | 0.81 | RAB9A (0.72) | RAB9AKMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3788716 | 0.80 | SMN1; SMN2 (0.58) | KMT2AMEN1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL3788319 | 0.80 | KDM4E (0.59) | RAB9AKMT2AMEN1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010143803-A2 | NEW NICOTINAMIDE DERIVATIVES WITH ANTI-ANDROGEN EFFECTS, PROCESSES OF PREPARING, AND ANTIANDROGENS COMPRISING THE SAME | INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) | 2010-12-16 | — | — | WO | claimed |
| WO-2010143803-A2 | NEW NICOTINAMIDE DERIVATIVES WITH ANTI-ANDROGEN EFFECTS, PROCESSES OF PREPARING, AND ANTIANDROGENS COMPRISING THE SAME | INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) | 2010-12-16 | — | — | WO | disclosed |
| WO-2010143803-A2 | NEW NICOTINAMIDE DERIVATIVES WITH ANTI-ANDROGEN EFFECTS, PROCESSES OF PREPARING, AND ANTIANDROGENS COMPRISING THE SAME | INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) | 2010-12-16 | — | — | WO | disclosed |