Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.52 |
| ▸ | EGFR | P00533 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3760532 | 0.94 | ALDH1A1 (0.57) | KMT2AALDH1A1EGFRHTTRAB9A | |
| SCHEMBL3791796 | 0.86 | HTT (0.53) | KMT2AALDH1A1HTTL3MBTL1LMNA | |
| SCHEMBL3755932 | 0.85 | ALDH1A1 (0.56) | ALDH1A1EGFRHTTRAB9AL3MBTL1 | |
| SCHEMBL3761284 | 0.83 | HTT (0.58) | KMT2AALDH1A1HTTL3MBTL1LMNA | |
| SCHEMBL3785819 | 0.82 | P2RX7 (0.44) | KMT2AALDH1A1HTTLMNAP2RX7 | |
| SCHEMBL3765565 | 0.79 | P2RX7 (0.48) | KMT2AALDH1A1HTTLMNAP2RX7 | |
| SCHEMBL3762001 | 0.79 | KMT2A (0.50) | KMT2AALDH1A1LMNAGAAP2RX7 | |
| SCHEMBL3757585 | 0.79 | P2RX7 (0.47) | KMT2AALDH1A1HTTRAB9AL3MBTL1 | |
| SCHEMBL3755688 | 0.77 | KMT2A (0.47) | KMT2AALDH1A1GAAP2RX7 | |
| SCHEMBL3760814 | 0.76 | ALDH1A1 (0.59) | KMT2AALDH1A1HTTL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138828-A2 | POTASSIUM CHANNEL MODULATORS | ABBOTT LABORATORIES (US) | 2010-12-02 | — | — | WO | disclosed |