Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3790388 | 0.88 | CA2 (0.41) | CA2CA9CA1 | |
| SCHEMBL3788536 | 0.86 | CA2 (0.39) | CA2CA9CA1 | |
| SCHEMBL23150453 | 0.84 | CA2 (0.38) | CA2CA9CA1 | |
| SCHEMBL14181931 | 0.78 | CA2 (0.39) | CA2CA9CA1 | |
| SCHEMBL1032931 | 0.78 | CA2 (0.47) | CA2CA9CA1 | |
| SCHEMBL17596857 | 0.78 | TSHR (0.40) | CA2CA9CA1 | |
| SCHEMBL577322 | 0.77 | CA2 (0.35) | CA2CA9CA1 | |
| SCHEMBL3789621 | 0.75 | CA2 (0.37) | CA2CA1 | |
| SCHEMBL20553030 | 0.75 | CA1 (0.34) | CA2CA1 | |
| SCHEMBL14052987 | 0.75 | CA1 (0.34) | CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160244435-A1 | EXPANDED THERAPEUTIC POTENTIAL IN NITROHETEROARYL ANTIMICROBIALS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-08-25 | — | — | US | disclosed |
| US-20160244435-A1 | EXPANDED THERAPEUTIC POTENTIAL IN NITROHETEROARYL ANTIMICROBIALS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-08-25 | — | — | US | disclosed |
| EP-3010345-A1 | EXPANDED THERAPEUTIC POTENTIAL IN NITROHETEROARYL ANTIMICROBIALS | The Regents of The University of California (US) | 2016-04-27 | — | — | EP | disclosed |
| WO-2014205414-A1 | EXPANDED THERAPEUTIC POTENTIAL IN NITROHETEROARYL ANTIMICROBIALS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-12-24 | — | — | WO | disclosed |
| WO-2014205414-A1 | EXPANDED THERAPEUTIC POTENTIAL IN NITROHETEROARYL ANTIMICROBIALS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-12-24 | — | — | WO | disclosed |
| WO-2010118711-A2 | NOVEL HELQUATS, THEIR PRECURSORS AND METHOD OF PREPARATION THEREOF | Ústav organické chemie a biochemie Akademie ved Ceské republiky, v.v.i. (CZ) | 2010-10-21 | — | — | WO | disclosed |
| US-5208244-A | Administering substituted enol lactones | WASHINGTON UNIVERSITY (US) | 1993-05-04 | — | — | US | disclosed |
| US-5187174-A | Biological antigrowth agents | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1993-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160244435-A1 | EXPANDED THERAPEUTIC POTENTIAL IN NITROHETEROARYL ANTIMICROBIALS | NQO1, TXN2, MPO | CA2 4271/4885CA9 4167/4885CA1 4847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.