SCHEMBL3786079

SCHEMBL3786079

CCCO[Si](OCCC)(OCCC)C(C)S

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11783212 0.87 ADRB2 (0.35) HSD17B10
SCHEMBL11785287 0.85 USP2 (0.35)
SCHEMBL306668 0.80 LMNA (0.32)
SCHEMBL426715 0.80 HSD17B10 (0.35) HSD17B10
SCHEMBL105839 0.80 HSD17B10 (0.35) HSD17B10
SCHEMBL3687057 0.79
SCHEMBL1840997 0.79
SCHEMBL28309138 0.78 LMNA (0.30)
SCHEMBL23526431 0.77
SCHEMBL11455676 0.76 HSD17B10 (0.37) HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113024789-B Crosslinked polymer micelle and preparation method and application thereof 福建省紫杉园药业有限责任公司 2023-01-06 CN claimed
CN-111423878-B Fluorescent magnetic composite nano-particles, preparation method thereof and biological probe prepared from fluorescent magnetic composite nano-particles 山东交通学院 2022-11-08 CN claimed
CN-111423878-A Fluorescent magnetic composite nano-particles, preparation method thereof and biological probe prepared from fluorescent magnetic composite nano-particles 山东交通学院 2020-07-17 CN claimed
EP-1208165-B1 PROCESS FOR PRODUCING CHEMICALLY MODIFIED FILLERS PPG IND OHIO INC (US) 2007-12-19 EP claimed
EP-1208164-B1 PROCESS FOR PRODUCING CHEMICALLY TREATED FILLERS PPG IND OHIO INC (US) 2007-10-24 EP claimed
CN-1312228-C Process for producing chemically modified fillers PPG IND OHIO INC (US) 2007-04-25 CN claimed
CN-1312229-C Process for producing chemically treated fillers PPG IND OHIO INC (US) 2007-04-25 CN claimed
US-7163975-B2 Tire with compound of rubber composition comprised of silanol and/or siloxy functionalized elastomer and silica THE GOODYEAR TIRE & RUBBER COMPANY (US) 2007-01-16 US claimed
US-7071251-B2 Tire with component comprised of rubber composite of styrene/butadiene elastomer containing pendent silanol and/or siloxy groups THE GOODYEAR TIRE & RUBBER COMPANY (US) 2006-07-04 US claimed
US-6998448-B2 Tire with tread of CIS 1,4-polybutadiene rich rubber composition which contains a functional styrene/butadiene elastomer, silica and coupling agent THE GOODYEAR TIRE & RUBBER COMPANY (US) 2006-02-14 US claimed
US-20040054065-A1 Tire with tread of CIS 1,4-polybutadiene rich rubber composition which contains a functional styrene/butadiene elastomer, silica and coupling agent GOODYEAR TIRE & RUBBER COMPANY, THE 2004-03-18 US claimed
US-20040054032-A1 Tire with component of rubber composition comprised of silanol and/or siloxy functionalized elastomer and silica GOODYEAR TIRE & RUBBER COMPANY, THE 2004-03-18 US claimed
EP-1398347-A1 Tire with tread of cis 1,4-polybutadiene-rich rubber composition which contains a functional styrene/butadiene elastomer, silica and coupling agent THE GOODYEAR TIRE & RUBBER COMPANY (US) 2004-03-17 EP claimed
CN-1374989-A Process for producing chemically treated fillers PPG IND OHIO INC (US) 2002-10-16 CN claimed
CN-1374988-A Process for producing chemically modified fillers PPG IND OHIO INC (US) 2002-10-16 CN claimed
US-6455613-B1 SILICA AGGREGATES BLENDED WITH DIENE RUBBER TOGETHER WITH ASILICA COUPLER HAVING A GROUP REACTIVE WITH HYDROXYL GROUP ON THE SURFACE OF FUMED SILICA AND ANOTHER GROUP INTERACTIVE WITH DIENE RUBBER, SUCH AS ORGANOSULFURSILANE OR PRETREATED THE GOODYEAR TIRE & RUBBER COMPANY 2002-09-24 US claimed
EP-1208164-A1 PROCESS FOR PRODUCING CHEMICALLY TREATED FILLERS PPG Industries Ohio Inc. (US) 2002-05-29 EP claimed
EP-1208165-A1 PROCESS FOR PRODUCING CHEMICALLY MODIFIED FILLERS PPG Industries Ohio, Inc. (US) 2002-05-29 EP claimed
WO-2001021715-A1 PROCESS FOR PRODUCING CHEMICALLY MODIFIED FILLERS PPG INDUSTRIES OHIO, INC. (US) 2001-03-29 WO claimed
WO-2001012733-A1 PROCESS FOR PRODUCING CHEMICALLY TREATED FILLERS PPG INDUSTRIES OHIO, INC. (US) 2001-02-22 WO claimed