Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.48 |
| ▸ | BACE1 | P56817 | 3/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | BCR | P11274 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3796574 | 0.83 | PTGS2 (0.46) | ALDH1A1KDM4ESMN1; SMN2HPGDPTGS2 | |
| SCHEMBL3789193 | 0.80 | PTGS2 (0.45) | ALDH1A1KDM4ESMN1; SMN2HPGDPTGS2 | |
| SCHEMBL1573422 | 0.78 | KDM4E (0.50) | ALDH1A1KDM4EHPGDPTGS2BACE1 | |
| SCHEMBL20323146 | 0.77 | BACE1 (0.59) | ALDH1A1KDM4ESMN1; SMN2HPGDPTGS2 | |
| SCHEMBL7093922 | 0.75 | ALDH1A1 (0.51) | ALDH1A1KDM4ESMN1; SMN2HPGDPTGS2 | |
| SCHEMBL5904146 | 0.74 | PDE10A (0.60) | ALDH1A1KDM4EMAPTKMT2AMAP2K1 | |
| SCHEMBL7039067 | 0.74 | PTGS2 (0.72) | ALDH1A1KDM4ESMN1; SMN2HPGDPTGS2 | |
| SCHEMBL28260523 | 0.74 | GCGR (0.64) | ALDH1A1KDM4ESMN1; SMN2MAPTMEN1 | |
| SCHEMBL7042910 | 0.74 | PTGS2 (0.72) | ALDH1A1KDM4ESMN1; SMN2HPGDPTGS2 | |
| SCHEMBL15057905 | 0.73 | PTGS2 (0.60) | ALDH1A1KDM4EHPGDPTGS2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093595-A1 | FUNGICIDAL 2-PYRIDONES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-08-19 | — | — | WO | claimed |
| WO-2010093595-A1 | FUNGICIDAL 2-PYRIDONES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-08-19 | — | — | WO | disclosed |