Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | P4HB | P07237 | 1/20 | 0.33 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.33 |
| ▸ | ABAT | P80404 | 1/20 | 0.33 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.32 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.32 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3709305 | 0.91 | SNCA (0.34) | SNCACYP2A6 | |
| SCHEMBL4264297 | 0.84 | SNCA (0.44) | SNCA | |
| SCHEMBL28484974 | 0.83 | CYP2A6 (0.35) | CYP2A6ALDH1A1TYRCYP2A13HSD17B10 | |
| SCHEMBL17940978 | 0.82 | ALDH1A1 (0.39) | SNCAALDH1A1P4HBTDP1 | |
| SCHEMBL6259290 | 0.79 | ALDH1A1 (0.40) | CYP2A6ALDH1A1TYRCYP2A13HSD17B10 | |
| SCHEMBL4257326 | 0.79 | SNCA (0.48) | SNCA | |
| SCHEMBL12370809 | 0.77 | SNCA (0.41) | SNCATDP1 | |
| SCHEMBL13188128 | 0.77 | SNCA (0.40) | SNCA | |
| SCHEMBL16399033 | 0.76 | ALDH1A1 (0.39) | CYP2A6ALDH1A1HSD17B10ALDH1A3KDM4E | |
| SCHEMBL18002123 | 0.76 | SNCA (0.30) | SNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8492577-B2 | Process for preparation of valsartan intermediate | HETERO RESEARCH FOUNDATION (IN) | 2013-07-23 | — | — | US | disclosed |
| US-20110237822-A1 | PROCESS FOR PREPARATION OF VALSARTAN INTERMEDIATE | HETERO RESEARCH FOUNDATION (IN) | 2011-09-29 | — | — | US | disclosed |
| EP-2260018-A2 | PROCESS FOR PREPARATION OF VALSARTAN INTERMEDIATE | Hetero Research Foundation (IN) | 2010-12-15 | — | — | EP | disclosed |
| EP-2246329-A1 | 4(1H)-pyridinone derivatives and their use as antimalaria agents | Glaxo Group Limited (GB) | 2010-11-03 | — | — | EP | disclosed |
| WO-2010081904-A1 | 4 ( 1H) -PYRIDINONE DERIVATIVES AND THEIR USE AS ANTIMALARIA AGENTS | GLAXO GROUP LIMITED (GB) | 2010-07-22 | — | — | WO | disclosed |
| US-7635595-B2 | Fluorescent probes for saccharrides | LAKOWICZ JOSEPH R | 2009-12-22 | — | — | US | disclosed |
| US-7635595-B2 | Fluorescent probes for saccharrides | LAKOWICZ JOSEPH R | 2009-12-22 | — | — | US | disclosed |
| US-7632954-B2 | Sym-N-(n-hexyl)-5-bromotriindole; Sym-N-(n-hexyl)-5-phenyltriindole; Sym-N-(n-hexyl)-[2-cyano-2-(4-pyridyl)vinyl]triindole; electrification preventions, electrification controls, capacitors, batteries, chemical sensors, displays, organic EL materials, solar cells, photodiodes, phototransistors; fibers | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2009-12-15 | — | — | US | disclosed |
| WO-2009125416-A2 | PROCESS FOR PREPARATION OF VALSARTAN INTERMEDIATE | HETERO RESEARCH FOUNDATION (IN) | 2009-10-15 | — | — | WO | disclosed |
| US-20090124577-A1 | Intermediate Compounds for the Preparation of an Angiotensin II Receptor Antagonist | ENANTIA SI | 2009-05-14 | — | — | US | disclosed |
| EP-1838681-A2 | INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF AN ANGIOTENSIN II RECEPTOR AND PROCESS FOR THE PREPARATION OF VALSARTAN | Enantia, S.L. (ES) | 2007-10-03 | — | — | EP | disclosed |
| US-20070191455-A1 | Substituted sym-triindole | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-08-16 | — | — | US | disclosed |
| WO-2007071750-A1 | INTERMEDIATES AND PROCESSES FOR THE PREPARATION OF VALSARTAN | ENANTIA, S.L. (ES) | 2007-06-28 | — | — | WO | disclosed |
| US-20070112008-A1 | Saframycins, analogues and uses thereof | MYERS ANDREW G | 2007-05-17 | — | — | US | disclosed |
| US-20070112008-A1 | Saframycins, analogues and uses thereof | MYERS ANDREW G | 2007-05-17 | — | — | US | disclosed |
| WO-2006067216-A2 | INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF AN ANGIOTENSIN II RECEPTOR AND PROCESS FOR THE PREPARATION OF VALSARTAN | ENANTIA, S. L. (ES) | 2006-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124577-A1 | Intermediate Compounds for the Preparation of an Angiotensin II Receptor Antagonist | AGTR2, AGTR1, ACE | SNCA 3613/4885CYP2A6 228/4885ALDH1A1 1491/4885 |
| US-20070112008-A1 | Saframycins, analogues and uses thereof | MYC, MAN1B1, MRPS18A | SNCA 3426/4885CYP2A6 1128/4885ALDH1A1 1074/4885 |
| US-20110237822-A1 | PROCESS FOR PREPARATION OF VALSARTAN INTERMEDIATE | REN, AGT, ACE | SNCA 2333/4885CYP2A6 72/4885ALDH1A1 1185/4885 |
| US-20070191455-A1 | Substituted sym-triindole | RTF1, ETF1, RTF2 | SNCA 2272/4885CYP2A6 4353/4885ALDH1A1 1091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.