Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3792814 | 0.82 | TSHR (0.50) | TSHRCYP3A4ALDH1A1GAACA12 | |
| SCHEMBL11593134 | 0.81 | CYP3A4 (0.54) | TSHRCYP3A4ALDH1A1MAPK1GAA | |
| SCHEMBL30667273 | 0.78 | EPHX1 (0.52) | CYP3A4ALDH1A1GAACA2CA4 | |
| SCHEMBL856883 | 0.78 | EPHX1 (0.52) | CYP3A4ALDH1A1GAACA2CA4 | |
| SCHEMBL13548437 | 0.78 | TDP1 (0.46) | TSHRCYP3A4ALDH1A1ALOX15RECQL | |
| SCHEMBL30724396 | 0.78 | TDP1 (0.46) | TSHRCYP3A4ALDH1A1ALOX15RECQL | |
| SCHEMBL3791559 | 0.77 | CYP3A4 (0.45) | TSHRCYP3A4ALDH1A1MAPK1GAA | |
| Hydrochloric Acid SCHEMBL11296739 | 0.76 | TDP1 (0.44) | TSHRCYP3A4ALDH1A1ALOX15RECQL | |
| Hydrochloric Acid SCHEMBL1027315 | 0.76 | EPHX1 (0.50) | CYP3A4ALDH1A1GAACA2CA4 | |
| SCHEMBL18334947 | 0.75 | CYP3A4 (0.49) | TSHRCYP3A4ALDH1A1MAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0146350-A2 | Hair treatment composition | UNILEVER PLC (GB) | 1985-06-26 | — | — | EP | claimed |
| WO-2017038838-A1 | NOVEL PYRAZOLO[3,4-d]PYRIMIDINE COMPOUND OR SALT THEREOF | 大鵬薬品工業株式会社 | 2017-03-09 | — | — | WO | disclosed |
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| EP-0640334-B1 | Hair coloring composition | BRISTOL MYERS SQUIBB CO (US) | 2001-12-12 | — | — | EP | disclosed |
| CN-1070696-C | Process and kit for dyeing hair | BRISTOL MYERS SQUIBO CO (US) | 2001-09-12 | — | — | CN | disclosed |
| CN-1070048-C | Hair coloring composition | BRISTOL MYERS SQUIBB CO (US) | 2001-08-29 | — | — | CN | disclosed |
| EP-0658339-B1 | Process and kit for dyeing hair | BRISTOL MYERS SQUIBB CO (US) | 2000-06-07 | — | — | EP | disclosed |
| EP-0658093-B1 | PROCESS AND KIT FOR DYEING HAIR | BRISTOL MYERS SQUIBB CO (US) | 2000-06-07 | — | — | EP | disclosed |
| CN-1050992-C | Method for dyeing hair and complete set of hair-dyestuff | BRISTOL MYERS SQUIBB CO LTD (US) | 2000-04-05 | — | — | CN | disclosed |
| EP-0621029-A1 | Use of metal salts and chelates together with chlorites as oxidants in hair coloring | Bristol-Myers Squibb Company (US) | 1994-10-26 | — | — | EP | disclosed |
| EP-0658093-A4 | PROCESS AND KIT FOR DYEING HAIR. | BRISTOL MYERS SQUIBB CO (US) | 1994-09-23 | — | — | EP | disclosed |
| CN-1074113-A | Hair dyeing method and complete set of hair-dyestuff | BRISTOL MILS SQIB CO LTD (US) | 1993-07-14 | — | — | CN | disclosed |
| WO-1993005759-A1 | PROCESS AND KIT FOR DYEING HAIR | BRISTOL-MYERS SQUIBB COMPANY (US) | 1993-04-01 | — | — | WO | disclosed |
| EP-0399746-B1 | USE OF CHLORITES AS OXIDANTS IN HAIR COLORING | Bristol-Myers Squibb Company (US) | 1993-03-10 | — | — | EP | disclosed |
| EP-0507448-A2 | Oxidative hair dyeing process with catalytic pretreatment | Bristol-Myers Squibb Company (US) | 1992-10-07 | — | — | EP | disclosed |
| EP-0399746-A1 | Use of chlorites as oxidants in hair coloring | Bristol-Myers Squibb Company (US) | 1990-11-28 | — | — | EP | disclosed |
| EP-0146350-A2 | Hair treatment composition | UNILEVER PLC (GB) | 1985-06-26 | — | — | EP | disclosed |
| US-4295848-A | Composition for hair dyeing which contains a para base and an ortho base | L'OREAL (FR) | 1981-10-20 | — | — | US | disclosed |
| US-4268264-A | ORTHO PRECURSORS SELECTED FROM AROMATIC DIAMINES, AMINOPHENOL, DIPHENOL, AND PHENYLENEDIAMINE | L'OREAL (FR) | 1981-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | TSHR 1688/4885CYP3A4 177/4885ALDH1A1 4339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.