Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.52 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30667273 | 1.00 | EPHX1 (0.52) | EPHX1EPHX2RAPGEF4CYP3A4APEX1 | |
| Hydrochloric Acid SCHEMBL1027315 | 0.97 | EPHX1 (0.50) | EPHX1EPHX2RAPGEF4CYP3A4APEX1 | |
| SCHEMBL3786506 | 0.80 | ALDH1A1 (0.37) | EPHX1EPHX2RAPGEF4CYP3A4APEX1 | |
| SCHEMBL3624226 | 0.80 | RAPGEF4 (0.57) | RAPGEF4CYP3A4MEN1MAPTKMT2A | |
| SCHEMBL3781932 | 0.80 | ALDH1A1 (0.37) | EPHX1EPHX2RAPGEF4CYP3A4APEX1 | |
| SCHEMBL10979467 | 0.80 | RAPGEF4 (0.42) | RAPGEF4MEN1MAPTKMT2ALMNA | |
| SCHEMBL24267985 | 0.78 | MAPT (0.52) | CYP3A4MEN1MAPTKMT2ALMNA | |
| Hydrochloric Acid SCHEMBL27585338 | 0.78 | RAPGEF4 (0.55) | RAPGEF4CYP3A4MEN1MAPTKMT2A | |
| SCHEMBL3786386 | 0.78 | TSHR (0.50) | CYP3A4CA2CA4CA5ACA9 | |
| SCHEMBL10001895 | 0.78 | HSD17B10 (0.50) | EPHX2CYP3A4CA2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 259 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117886718-B | Preparation method of high-selectivity asymmetric urea compound and asymmetric urea compound | 内蒙古工业大学 | 2024-05-24 | — | — | CN | claimed |
| CN-117886718-A | Preparation method of high-selectivity asymmetric urea compound and asymmetric urea compound | 内蒙古工业大学 | 2024-04-16 | — | — | CN | claimed |
| WO-2017160709-A1 | WATER SOLUBLE HALOANILIDE CALCIUM-RELEASE CALCIUM CHANNEL INHIBITORY COMPOUNDS AND METHODS TO CONTROL BONE EROSION AND INFLAMMATION ASSOCIATED WITH ARTHRITIDES | WEST VIRGINIA UNIVERSITY (US) | 2017-09-21 | — | — | WO | claimed |
| US-20170260128-A1 | Water Soluble Haloanilide Calcium-Release Calcium Channel Inhibitory Compounds and Methods to Control Bone Erosion and Inflammation Associated with Arthritides | WEST VIRGINIA UNIVERSITY | 2017-09-14 | — | — | US | claimed |
| EP-2430023-B1 | AZACYCLIC SPIRODERIVATIVES AS HSL INHIBITORS | HOFFMANN LA ROCHE (CH) | 2013-12-11 | — | — | EP | claimed |
| US-20110053985-A1 | NOVEL PIPERIDINE-4-CARBOXYLIC ACID PHENYL-ALKYL-AMIDE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2011-03-03 | — | — | US | claimed |
| WO-2010130665-A1 | AZACYCLIC SPIRODERIVATIVES AS HSL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-11-18 | — | — | WO | claimed |
| US-20100292212-A1 | NEW AZACYCLIC DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2010-11-18 | — | — | US | claimed |
| EP-2245011-A1 | NOVEL PIPERIDINE-4-CARBOXYLIC ACID PHENYL-ALKYL-AMIDE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NeuroSearch A/S (DK) | 2010-11-03 | — | — | EP | claimed |
| WO-2009090173-A1 | NOVEL PIPERIDINE-4-CARBOXYLIC ACID PHENYL-ALKYL-AMIDE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2009-07-23 | — | — | WO | claimed |
| EP-1236720-B1 | Sulfonyl pyridazinone compounds useful as aldose reductase inhibitors | PFIZER PROD INC (US) | 2005-06-15 | — | — | EP | claimed |
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | claimed |
| US-6730674-B2 | ANTIDIABETIC AGENTS | PFIZER INC | 2004-05-04 | — | — | US | claimed |
| US-20030004139-A1 | Sulfonyl pyridazinone compounds useful as aldose reductase inhibitors | MARTIN WILLIAM H (US) | 2003-01-02 | — | — | US | claimed |
| EP-1236720-A1 | Sulfonyl pyridazinone compounds useful as aldose reductase inhibitors | Pfizer Products Inc. (US) | 2002-09-04 | — | — | EP | claimed |
| EP-4499641-A1 | A3 ADENOSINE RECEPTOR POSITIVE ALLOSTERIC MODULATORS | The United States of America, as represented by the Secretary, Department of Health and Human Services (US) | 2025-02-05 | — | — | EP | disclosed |
| WO-2024123663-A1 | ANTIMICROBIAL COMPOUNDS | SRI INTERNATIONAL (US) | 2024-06-13 | — | — | WO | disclosed |
| US-4286983-A | INCLUDING COMPOUNDS OF THE N-PHENYL-N',N'-DIETHYL ALKYLENEDIAMINE TYPE | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1981-09-01 | — | — | US | disclosed |
| EP-0002721-A2 | Process for preparing hydrazines | BAYER AG (DE) | 1979-07-11 | — | — | EP | disclosed |
| US-4101575-A | FUNGICIDES, BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1978-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053985-A1 | NOVEL PIPERIDINE-4-CARBOXYLIC ACID PHENYL-ALKYL-AMIDE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | SLC18A2, SLC6A2, SLC18A3 | EPHX1 1214/4885EPHX2 1328/4885RAPGEF4 344/4885 |
| US-20170260128-A1 | Water Soluble Haloanilide Calcium-Release Calcium Channel Inhibitory Compounds and Methods to Control Bone Erosion and Inflammation Associated with Arthritides | TRPV3, TRPV6, ORAI1 | EPHX1 3235/4885EPHX2 2833/4885RAPGEF4 1076/4885 |
| US-20100292212-A1 | NEW AZACYCLIC DERIVATIVES | GPR119, LDLR, LPL | EPHX1 1665/4885EPHX2 2736/4885RAPGEF4 2779/4885 |
| US-20030004139-A1 | Sulfonyl pyridazinone compounds useful as aldose reductase inhibitors | ALDOA, PDXK, AKR1B1 | EPHX1 1213/4885EPHX2 1479/4885RAPGEF4 3289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.