Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | CXCR2 | P25025 | 5/20 | 0.35 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.35 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1789519 | 0.82 | MEN1 (0.58) | MEN1KMT2ASMN1; SMN2KEAP1CXCR2 | |
| SCHEMBL29956764 | 0.82 | MEN1 (0.58) | MEN1KMT2ASMN1; SMN2KEAP1CXCR2 | |
| SCHEMBL31419627 | 0.80 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2KEAP1CXCR2 | |
| SCHEMBL29957894 | 0.80 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2KEAP1CXCR2 | |
| SCHEMBL3790283 | 0.79 | MEN1 (0.48) | MEN1KMT2ASMN1; SMN2KEAP1CXCR2 | |
| SCHEMBL3794880 | 0.76 | ALDH1A1 (0.47) | MEN1KMT2ASMN1; SMN2KEAP1ALDH1A1 | |
| SCHEMBL10732362 | 0.73 | KMT2A (0.52) | MEN1KMT2ASMN1; SMN2KEAP1CXCR2 | |
| SCHEMBL30689988 | 0.73 | KMT2A (0.47) | MEN1KMT2ASMN1; SMN2KEAP1CXCR2 | |
| SCHEMBL188296 | 0.73 | MEN1 (0.65) | MEN1KMT2ASMN1; SMN2KEAP1CXCR2 | |
| SCHEMBL6646866 | 0.71 | KMT2A (0.53) | MEN1KMT2ASMN1; SMN2KEAP1CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | MEN1 174/4885KMT2A 1474/4885SMN1; SMN2 4524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.