Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | MMP1 | P03956 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
| ▸ | F2 | P00734 | 3/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5365664 | 0.88 | CA1 (0.52) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL9306552 | 0.88 | MMP8 (0.55) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL1568905 | 0.87 | CA1 (0.55) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL8650577 | 0.85 | CA1 (0.50) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL11571366 | 0.85 | MMP8 (0.52) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL11855189 | 0.85 | CA2 (0.47) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL10670385 | 0.84 | CA1 (0.55) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL3423928 | 0.84 | CA2 (0.59) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL13432884 | 0.84 | CA1 (0.41) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL10673325 | 0.84 | CA2 (0.52) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160010086-A1 | OLIGOMERIC COMPOUNDS AND EXCIPIENTS | ISIS PHARMACEUTICALS, INC. (US) | 2016-01-14 | — | — | US | claimed |
| WO-2010091301-A1 | OLIGOMERIC COMPOUNDS AND EXCIPIENTS | ISIS PHARMACEUTICALS, INC. (US) | 2010-08-12 | — | — | WO | claimed |
| US-20160010086-A1 | OLIGOMERIC COMPOUNDS AND EXCIPIENTS | ISIS PHARMACEUTICALS, INC. (US) | 2016-01-14 | — | — | US | disclosed |
| US-20120264806-A1 | OLIGOMERIC COMPOUNDS AND EXCIPIENTS | ISIS PHARMACEUTICALS, INC. | 2012-10-18 | — | — | US | disclosed |
| US-3989656-A | Dextran-alkyl methacrylate graft composition for contact lens and corneas | KARME COMPANY LTD. (JA) | 1976-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160010086-A1 | OLIGOMERIC COMPOUNDS AND EXCIPIENTS | HNRNPA3, SNRPE, HNRNPA1 | CA1 4206/4885CA2 3107/4885MMP1 3405/4885 |
| US-20120264806-A1 | OLIGOMERIC COMPOUNDS AND EXCIPIENTS | HNRNPA3, SNRPE, HNRNPA1 | CA1 4206/4885CA2 3107/4885MMP1 3405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.