Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | AKT1 | P31749 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15884467 | 0.86 | ALDH1A1 (0.59) | HDAC2HDAC8HDAC6CYP2C19POLB | |
| SCHEMBL6180339 | 0.84 | CA12 (0.52) | HDAC8HDAC6CA12CA1CA7 | |
| SCHEMBL3786569 | 0.82 | HDAC1 (0.53) | HDAC6HTTHDAC1GAAALDH1A1 | |
| SCHEMBL1261932 | 0.81 | SYK (0.50) | CA12CA1CA7CA14MAPT | |
| SCHEMBL27966342 | 0.79 | SYK (0.48) | CA12CA1CA7CA14MAPT | |
| SCHEMBL20597404 | 0.79 | HDAC2 (0.73) | HDAC2HDAC8HDAC6MAPTHTT | |
| SCHEMBL2246416 | 0.79 | ATM (0.56) | CA12CA1CA7CA14MAPT | |
| SCHEMBL3786555 | 0.79 | TDP1 (0.50) | CA12CA1CA7CA14ALDH1A1 | |
| SCHEMBL1380801 | 0.78 | TDP1 (0.61) | HDAC2HDAC8HDAC6MAPTHTT | |
| SCHEMBL10592370 | 0.78 | HDAC2 (0.61) | HDAC2HDAC8HDAC6CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102775471-B | Method for synthesizing cholecystokinin octapeptide by combining solid phase method and liquid phase method | GL BIOCHEM SHANGHAI CO LTD | 2013-10-30 | — | — | CN | claimed |
| CN-102775471-A | Method for synthesizing cholecystokinin octapeptide by combining solid phase method and liquid phase method | GL BIOCHEM SHANGHAI CO LTD | 2012-11-14 | — | — | CN | claimed |
| CN-114174312-A | Air-stable Ni (0) -olefin complexes and their use as catalysts or precatalysts | 科勒研究有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-103626845-B | As the aryl of glycogen phosphorylase inhibitors and pyrroles-2-methane amide dipeptidase derivant, its preparation method and medicinal use | CHENGDE MEDICAL UNIVERSITY (CN) | 2015-11-11 | — | — | CN | disclosed |
| CN-103626845-A | Arylpyrrole-2-formamide dipeptide derivatives serving as glycogen phosphorylase inhibitor and preparation method and medical application thereof | CHENGDE MEDICAL UNIVERSITY | 2014-03-12 | — | — | CN | disclosed |
| WO-2010024762-A1 | PREPARATION OF β-PHENYL-ISOSERINE DERIVATIVES | ORGANOCLICK AKTIEBOLAG (SE) | 2010-03-04 | — | — | WO | disclosed |