Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844769 | 0.92 | ADRB2 (0.49) | TDP1CA12CA1CA7CA14 | |
| SCHEMBL30678936 | 0.90 | ALOX5 (0.48) | CA12CA1CA7CA14CTSK | |
| SCHEMBL7101278 | 0.87 | CA2 (0.41) | CA1IDO1PPARGPPARA | |
| SCHEMBL3901264 | 0.86 | CA2 (0.40) | CA12CA1CA7CA14AKT1 | |
| SCHEMBL6942862 | 0.86 | CA12 (0.46) | CA12CA1CA7CA14CTSK | |
| SCHEMBL1948655 | 0.85 | CA12 (0.50) | CA12CA1CA7CA14CTSK | |
| SCHEMBL9006857 | 0.84 | TDP1 (0.56) | TDP1CA12CA7CA14ALDH1A1 | |
| SCHEMBL1380801 | 0.82 | TDP1 (0.61) | TDP1ALDH1A1KMT2AKEAP1 | |
| SCHEMBL23467154 | 0.80 | CA2 (0.45) | CA12CA1CA7CA14KMT2A | |
| SCHEMBL23859885 | 0.80 | CA1 (0.37) | CA12CA1CA7CA14CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109867630-A | - 1 receptor modulators of novel glp-1 | 赛尔基因第二国际有限公司 | 2019-06-11 | — | — | CN | disclosed |
| CN-105593225-B | novel GLP-1 receptor modulators | 赛尔基因第二国际有限公司 | 2019-04-16 | — | — | CN | disclosed |
| EP-3353145-A1 | PRODRUGS OF GAMMA-HYDROXYBUTYRIC ACID, COMPOSITIONS AND USES THEREOF | XW Laboratories Inc. (KY) | 2018-08-01 | — | — | EP | disclosed |
| WO-2017050259-A1 | PRODRUGS OF GAMMA-HYDROXYBUTYRIC ACID, COMPOSITIONS AND USES THEREOF | XW LABORATORIES INC. (KY) | 2017-03-30 | — | — | WO | disclosed |
| WO-2017049470-A1 | PRODRUGS OF GAMMA-HYDROXYBUTYRIC ACID, COMPOSITIONS AND USES THEREOF | XW LABORATORIES INC. (CN) | 2017-03-30 | — | — | WO | disclosed |
| WO-2010024762-A1 | PREPARATION OF β-PHENYL-ISOSERINE DERIVATIVES | ORGANOCLICK AKTIEBOLAG (SE) | 2010-03-04 | — | — | WO | disclosed |