Acetonitrile

Acetonitrile

SCHEMBL3786777

CC#N.Sc1ccc(-c2ccc(S)cc2)cc1

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.36
TRPV4 Q9HBA0 2/20 0.34
KIF11 P52732 2/20 0.34
ALDH1A1 P00352 1/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
MMP3 P08254 1/20 0.33
HAO1 Q9UJM8 1/20 0.33
CYP1A1 P04798 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP1B1 Q16678 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetonitrile SCHEMBL6565616 0.84
SCHEMBL31197555 0.80 IDO1 (0.50) IDO1ALDH1A1TP53CYP3A4TDP1
SCHEMBL63208 0.80 IDO1 (0.50) IDO1ALDH1A1TP53CYP3A4TDP1
SCHEMBL967694 0.80 IDO1 (0.50) IDO1ALDH1A1TP53CYP3A4TDP1
Acetonitrile SCHEMBL28407908 0.80 ALDH1A1 (0.48) IDO1TRPV4ALDH1A1TP53CYP3A4
SCHEMBL23624581 0.78 MMP3 (0.58) KIF11ALDH1A1MMP3
SCHEMBL6788032 0.78 MMP3 (0.58) KIF11ALDH1A1MMP3
Acetonitrile SCHEMBL27892450 0.78 CA3 (0.46) ALDH1A1CYP3A4MMP3
SCHEMBL9297301 0.77 IDO1 (0.47) IDO1ALDH1A1TP53CYP3A4TDP1
Benzenethiol SCHEMBL29028083 0.77 TSHR (0.41) IDO1TRPV4ALDH1A1CYP1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1157407-B1 METHODS UTILIZING SCANNING PROBE MICROSCOPE TIPS UNIV NORTHWESTERN (US) 2010-11-17 EP disclosed
EP-1292361-B1 METHODS UTILIZING SCANNING PROBE MICROSCOPE TIPS AND PRODUCTS THEREFOR OR PRODUCED THEREBY UNIV NORTHWESTERN (US) 2008-02-20 EP disclosed