Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25113324 | 0.98 | LPAR3 (0.44) | LPAR3LPAR2TSHRADORA1ABCC4 | |
| SCHEMBL13345367 | 0.96 | LPAR3 (0.41) | LPAR3LPAR2TSHRADORA1ABCC4 | |
| SCHEMBL19619508 | 0.91 | ALDH1A1 (0.35) | LPAR3LPAR2TSHRADORA1ALDH1A1 | |
| SCHEMBL16581595 | 0.89 | LPAR3 (0.50) | LPAR3LPAR2TSHRADORA1ABCC4 | |
| SCHEMBL16581539 | 0.89 | LPAR3 (0.50) | LPAR3LPAR2TSHRADORA1ABCC4 | |
| SCHEMBL22268773 | 0.88 | TSHR (0.37) | LPAR3LPAR2TSHRABCC4MAPT | |
| SCHEMBL22268682 | 0.87 | LPAR3 (0.37) | LPAR3LPAR2TSHRADORA1ALDH1A1 | |
| SCHEMBL16581541 | 0.86 | LPAR3 (0.46) | LPAR3LPAR2TSHRADORA1ABCC4 | |
| SCHEMBL2027305 | 0.86 | LPAR3 (0.52) | LPAR3LPAR2TSHRADORA1ABCC4 | |
| SCHEMBL891891 | 0.86 | LPAR3 (0.52) | LPAR3LPAR2TSHRADORA1ABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1607743-B1 | Silane molecules with pre-activated and protein-resistant functionalities and silane films comprising such molecules | IMEC (BE) | 2010-08-11 | — | — | EP | disclosed |
| US-7285674-B2 | Silane molecules with pre-activated and protein-resistant functionalities and silane films comprising such molecules | INTERUNIVERSITAIR MICROELEKTRONICA CENTRUM (IMEC) (BE) | 2007-10-23 | — | — | US | disclosed |
| EP-1607743-A1 | Silane molecules with pre-activated and protein-resistant functionalities and silane films comprising such molecules | INTERUNIVERSITAIR MICROELEKTRONICA CENTRUM ( IMEC) (BE) | 2005-12-21 | — | — | EP | disclosed |
| US-20050255514-A1 | Silane molecules with pre-activated and protein-resistant functionalities and silane films comprising such molecules | INTERUNIVERSITAIR MICROELEKTRONICA CENTRUM (IMEC) (BE) | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050255514-A1 | Silane molecules with pre-activated and protein-resistant functionalities and silane films comprising such molecules | YWHAH, YWHAE, YWHAB | LPAR3 3164/4885LPAR2 2649/4885TSHR 2351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.