YWHAB

14-3-3 protein beta/alpha · P31946 · YWHAB on Sugi Atlas →

108 patent compounds predicted against YWHAB, 83 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL2560739 SCHEMBL2560739 0.64 1/20
SCHEMBL9770486 SCHEMBL9770486 0.63 1/20
SCHEMBL9355431 SCHEMBL9355431 0.58 1/20
SCHEMBL31306499 SCHEMBL31306499 0.58 1/20
SCHEMBL31306496 SCHEMBL31306496 0.58 1/20
SCHEMBL9265091 SCHEMBL9265091 0.58 1/20
SCHEMBL31306425 SCHEMBL31306425 0.57 1/20
SCHEMBL6956890 SCHEMBL6956890 0.57 1/20
SCHEMBL15970722 SCHEMBL15970722 0.57 1/20
SCHEMBL4984042 SCHEMBL4984042 0.56 1/20
SCHEMBL11359120 SCHEMBL11359120 0.56 1/20
SCHEMBL17117361 SCHEMBL17117361 0.56 1/20
SCHEMBL31306465 SCHEMBL31306465 0.56 1/20
SCHEMBL31306475 SCHEMBL31306475 0.56 1/20
SCHEMBL31306483 SCHEMBL31306483 0.56 1/20
SCHEMBL4737461 SCHEMBL4737461 0.55 1/20
SCHEMBL9770555 SCHEMBL9770555 0.55 1/20
SCHEMBL31306445 SCHEMBL31306445 0.55 1/20
SCHEMBL5890282 SCHEMBL5890282 0.55 1/20
SCHEMBL9124718 SCHEMBL9124718 0.55 1/20

Clinical trials — most relevant to YWHAB by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
A Phase Ib/II Clinical Study Evaluating the Safety and Efficacy of Tislelizumab in Combination With Golidocitinib and Selinexor for the Treatment of R/R NKTCL PHASE1/PHASE2RECRUITING
Safety and Impact of Dasatinib on Viral Persistence and Inflammation in People With HIV Under Antiretroviral Treatment PHASE2COMPLETED
SCARFREE-001: Verteporfin for Scar Prevention PHASE2NOT_YET_RECRUITING
Effects of an Intensified Treatment With ACE-I,ATA II and Statins in Alport Syndrome PHASE2COMPLETED
Auranofin in Treating Patients With Recurrent Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer EARLY_PHASE1COMPLETED
Relationship of YWHAH Polymorphisms to Rheumatoid Arthritis Disease Severity nanCOMPLETED
IVM for Patients With Low Ovarian Response. Does it Improve IVFoutcomes and Does it Improve the Following IVF Cycle? nanUNKNOWN
Studying Protein Expression in Tissue Samples From Younger Patients With Rhabdomyosarcoma nanCOMPLETED
Semen Analysis Changes in Covid-19 Positivepatients nanCOMPLETED
Blood-based Biomarkers for the Prognosis of Sports Related Concussion nanCOMPLETED
Multi-Dimensional Genomic Dissection of Ring Chromosome 14 Syndrome nanACTIVE_NOT_RECRUITING
X-chromosome Inactivation, Epigenetics and the Transcriptome nanCOMPLETED
Molecular Biomarkers Associated With Degenerative Joint Disease in the Knee nanCOMPLETED
Aberrant Splicings Due to Microsatellite Instability in Colorectal Cancer : Physiopathological and Clinical Impact nanUNKNOWN
Expression of Fas Protein in Skin Biopsies of Participants With Scarring Alopecia nanCOMPLETED
Biomarkers in Idiopathic Juvenile Arthritis nanUNKNOWN
Epithelioid Haemangioendothelioma Observational Study nanRECRUITING
Unusual Infiltrative Patterns of Malignant Cells in Endometrial Carcinoma and Immunohistochemical Expression of P53 nanUNKNOWN
Screening for Hepatitis Virus B Protein X (HBx) in Colitis-associated Cancer (CAC) nanNOT_YET_RECRUITING
Molecular Associations With Reproductive Failure nanCOMPLETED
Amplification of Zinc Finger Protein 217 Gene in Multiple Myeloma nanUNKNOWN
Identification of Biomarkers for Early Detection of Pancreatic Cancer nanCOMPLETED
Proteomics to Identify Prognostic Markers After CPR and to Estimate Neurological Outcome nanCOMPLETED
Immunohistochemical Expression of EGFR in the Patients Having Oral Squamous Cell Carcinoma nanCOMPLETED
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA nanRECRUITING
Diet Intervention and GEnetic STudy (DIGEST-Pilot) nanUNKNOWN
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Family Blood Pressure Program - SAPPHIRe Network nanCOMPLETED
The Clinical Study of Sex Chromosome Variants nanCOMPLETED
Arterial Composition and Cardiovascular Outcome in DIabeteS nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a YWHAB binder may also engage these)

ProteinNameSimilarity
A4K2U9 1.000 A4K2U9 →
Q4R572 1.000 Q4R572 →
P68250 1.000 P68250 →
P35213 1.000 P35213 →
Q5ZLQ6 1.000 Q5ZLQ6 →
Q6UFZ8 1.000 Q6UFZ8 →
Q9CQV8 1.000 Q9CQV8 →
Q6UFZ9 1.000 Q6UFZ9 →
Q5R651 1.000 Q5R651 →
YWHAZ 14-3-3 protein zeta/delta 1.000 landscape →
Q5RC20 1.000 Q5RC20 →
YWHAG 14-3-3 protein gamma 1.000 landscape →
Q91896 1.000 Q91896 →
Q7T356 1.000 Q7T356 →
Q9C5W6 1.000 Q9C5W6 →
Q6PCG0 1.000 Q6PCG0 →
Q5ZKC9 1.000 Q5ZKC9 →
P68255 1.000 P68255 →
Q52M98 1.000 Q52M98 →
Q1HR36 1.000 Q1HR36 →
P63102 1.000 P63102 →
YWHAQ 14-3-3 protein theta 1.000 landscape →
Q5PRD0 1.000 Q5PRD0 →
Q6UFZ3 1.000 Q6UFZ3 →
P68252 1.000 P68252 →
P42649 1.000 P42649 →
P48347 1.000 P48347 →
Q6PC29 1.000 Q6PC29 →
P61982 1.000 P61982 →
P29361 1.000 P29361 →