Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3785091 | 0.90 | LTB4R (0.41) | LIPGDHFRCNR1CNR2CYSLTR2 | |
| SCHEMBL21243813 | 0.90 | LTB4R (0.44) | LIPGDHFRCYSLTR2CYSLTR1LTB4R | |
| SCHEMBL13446389 | 0.87 | LTB4R (0.42) | LIPGDHFRCYSLTR2CYSLTR1LTB4R | |
| SCHEMBL3774900 | 0.85 | TLR8 (0.36) | LIPGDHFRTP53MAPTSMN1; SMN2 | |
| SCHEMBL85738 | 0.84 | LTB4R (0.39) | LIPGDHFRCNR1CNR2LTB4R | |
| SCHEMBL85454 | 0.84 | LTB4R (0.39) | LIPGDHFRCNR1CNR2LTB4R | |
| SCHEMBL12921568 | 0.82 | MAPT (0.34) | GPR35TP53MAPTSMN1; SMN2ALOX15 | |
| SCHEMBL12921564 | 0.82 | MAPT (0.34) | GPR35TP53MAPTSMN1; SMN2ALOX15 | |
| SCHEMBL85694 | 0.82 | LTB4R (0.41) | LIPGDHFRCNR1CNR2LTB4R | |
| SCHEMBL85459 | 0.82 | LTB4R (0.41) | LIPGDHFRCNR1CNR2LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100331550-A1 | THIENOTHIOPHENE DERIVATIVES | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2010-12-30 | — | — | US | claimed |
| US-8329915-B2 | Thienothiophene derivatives | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2012-12-11 | — | — | US | disclosed |
| US-20100331550-A1 | THIENOTHIOPHENE DERIVATIVES | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331550-A1 | THIENOTHIOPHENE DERIVATIVES | TST, TPST2, TH | LIPG 4767/4885DHFR 221/4885CNR1 3750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.