Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 7/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.38 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD5 | P21918 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3792564 | 0.99 | EPHX2 (0.39) | EPHX2RIPK1HSD17B13ROCK2ROCK1 | |
| Sulfuric Acid SCHEMBL3794696 | 0.97 | EPHX2 (0.38) | EPHX2RIPK1HSD17B13ROCK2ROCK1 | |
| SCHEMBL13257878 | 0.89 | EPHX2 (0.41) | EPHX2RIPK1HSD17B13ROCK2ROCK1 | |
| SCHEMBL3790116 | 0.88 | EPHX2 (0.47) | EPHX2RIPK1HSD17B13ROCK2ROCK1 | |
| SCHEMBL3792366 | 0.87 | EPHX2 (0.49) | EPHX2ROCK2ROCK1 | |
| SCHEMBL3788832 | 0.85 | EPHX2 (0.40) | EPHX2RIPK1ROCK2ROCK1METTL3 | |
| SCHEMBL3790479 | 0.84 | GPR139 (0.41) | EPHX2RIPK1ROCK2ROCK1ALOX5 | |
| SCHEMBL3798917 | 0.84 | EPHX2 (0.39) | EPHX2RIPK1ROCK2ROCK1ALOX5 | |
| SCHEMBL3810168 | 0.81 | CD274 (0.42) | EPHX2EGLN1SCN9AKCNH2DRD2 | |
| SCHEMBL3788935 | 0.77 | EPHX2 (0.47) | EPHX2RIPK1HSD17B13ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010096722-A1 | 3-OXO-2, 3-DIHYDRO- [1,2, 4] TRIAZOLO [4, 3-A]PYRIDINES AS SOLUBLE EPOXIDE HYDROLASE (SEH) INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-26 | — | — | WO | disclosed |