Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 9/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.45 |
| ▸ | HSD17B13 | Q7Z5P4 | 3/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13257878 | 0.90 | EPHX2 (0.41) | EPHX2RIPK1HSD17B13ROCK2ROCK1 | |
| SCHEMBL3792366 | 0.89 | EPHX2 (0.49) | EPHX2ROCK2ROCK1 | |
| SCHEMBL3787484 | 0.88 | EPHX2 (0.39) | EPHX2RIPK1HSD17B13ROCK2ROCK1 | |
| Hydrochloric Acid SCHEMBL3792564 | 0.88 | EPHX2 (0.39) | EPHX2RIPK1HSD17B13ROCK2ROCK1 | |
| SCHEMBL3787655 | 0.87 | ROCK2 (0.48) | EPHX2RIPK1HSD17B13ROCK2ROCK1 | |
| SCHEMBL3796727 | 0.86 | EPHX2 (0.52) | EPHX2RIPK1HSD17B13ROCK2ROCK1 | |
| SCHEMBL3791214 | 0.86 | EPHX2 (0.45) | EPHX2RIPK1HSD17B13ROCK2ROCK1 | |
| Sulfuric Acid SCHEMBL3794696 | 0.86 | EPHX2 (0.38) | EPHX2RIPK1HSD17B13ROCK2ROCK1 | |
| SCHEMBL13258052 | 0.86 | EPHX2 (0.49) | EPHX2RIPK1HSD17B13ROCK2ROCK1 | |
| SCHEMBL3790889 | 0.86 | PPARG (0.52) | EPHX2RIPK1HSD17B13ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010096722-A1 | 3-OXO-2, 3-DIHYDRO- [1,2, 4] TRIAZOLO [4, 3-A]PYRIDINES AS SOLUBLE EPOXIDE HYDROLASE (SEH) INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-26 | — | — | WO | disclosed |
| WO-2010096722-A1 | 3-OXO-2, 3-DIHYDRO- [1,2, 4] TRIAZOLO [4, 3-A]PYRIDINES AS SOLUBLE EPOXIDE HYDROLASE (SEH) INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-26 | — | — | WO | disclosed |