Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK11 | Q15759 | 4/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.47 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHKA | P35790 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19698852 | 0.84 | MAPT (0.47) | MAPTSMN1; SMN2MAPK1ALDH1A1LMNA | |
| SCHEMBL29831689 | 0.83 | NOTUM (0.48) | MAPK11MAPK14CSNK1DMAPTSMN1; SMN2 | |
| SCHEMBL28489833 | 0.83 | NOTUM (0.48) | MAPK11MAPK14CSNK1DMAPTSMN1; SMN2 | |
| SCHEMBL29433183 | 0.82 | ALDH1A1 (0.45) | MAPTSMN1; SMN2MAPK1HSD17B10ALDH1A1 | |
| SCHEMBL1254512 | 0.82 | ALDH1A1 (0.45) | MAPTSMN1; SMN2MAPK1HSD17B10ALDH1A1 | |
| SCHEMBL30763243 | 0.80 | ALDH1A1 (0.44) | MAPTSMN1; SMN2MAPK1HSD17B10ALDH1A1 | |
| SCHEMBL27516508 | 0.80 | ALDH1A1 (0.44) | MAPTSMN1; SMN2MAPK1HSD17B10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2866856 | 0.80 | ALDH1A1 (0.44) | MAPTSMN1; SMN2MAPK1HSD17B10ALDH1A1 | |
| SCHEMBL27517786 | 0.80 | ALDH1A1 (0.44) | MAPTSMN1; SMN2MAPK1HSD17B10ALDH1A1 | |
| SCHEMBL30165671 | 0.79 | CYP2A6 (0.50) | MAPTSMN1; SMN2HSD17B10ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | MAPK11 3737/4885MAPK14 4123/4885CSNK1D 4867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.