Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3785779 | 0.80 | MAPT (0.43) | MAPTLMNAMEN1KMT2A | |
| SCHEMBL13018229 | 0.80 | MAPT (0.43) | MAPTLMNAMEN1KMT2A | |
| SCHEMBL13018236 | 0.76 | MAPT (0.43) | MAPTLMNAALDH1A1L3MBTL1MEN1 | |
| SCHEMBL3783970 | 0.75 | ABL1 (0.40) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL3779050 | 0.75 | MAPT (0.39) | MAPTLMNAMEN1KMT2A | |
| SCHEMBL16525942 | 0.71 | MGLL (0.38) | MAPTMEN1KMT2A | |
| SCHEMBL13018237 | 0.71 | GAA (0.39) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL27765388 | 0.70 | MAPT (0.57) | MAPTALDH1A1MAPK1TDP1L3MBTL1 | |
| SCHEMBL13018239 | 0.70 | IDO1 (0.44) | MAPTLMNAMEN1KMT2A | |
| SCHEMBL11737142 | 0.69 | CYP2C9 (0.57) | LMNATDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7858825-B2 | Acid and base stable diphenylmethanol derivatives and methods of use | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2010-12-28 | — | — | US | disclosed |
| US-20080200719-A1 | Acid and base stable diphenylmethanol derivatives and methods of use | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200719-A1 | Acid and base stable diphenylmethanol derivatives and methods of use | DPYD, DHODH, DAO | MAPT 1367/4885LMNA 693/4885ALDH1A1 258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.