Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 5/20 | 0.44 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.37 |
| ▸ | FYN | P06241 | 2/20 | 0.37 |
| ▸ | PGR | P06401 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13018229 | 0.78 | MAPT (0.43) | IDO1MAPTLMNACNR1KCNH2 | |
| SCHEMBL3785779 | 0.78 | MAPT (0.43) | IDO1MAPTLMNACNR1KCNH2 | |
| SCHEMBL13018236 | 0.75 | MAPT (0.43) | IDO1MAPTLMNACNR1KCNH2 | |
| SCHEMBL3783970 | 0.74 | ABL1 (0.40) | IDO1MAPTCYP2C9CYP3A4LMNA | |
| SCHEMBL3779050 | 0.74 | MAPT (0.39) | IDO1MAPTLMNACNR1MEN1 | |
| SCHEMBL16525942 | 0.72 | MGLL (0.38) | MAPTCNR1MEN1KMT2A | |
| SCHEMBL13018237 | 0.70 | GAA (0.39) | IDO1MAPTCNR1KCNH2MEN1 | |
| SCHEMBL3787689 | 0.70 | MAPT (0.43) | MAPTLMNAMEN1KMT2A | |
| SCHEMBL11137218 | 0.68 | ADRA2C (0.51) | IDO1ADRA2CMAPTCYP2C9CYP3A4 | |
| SCHEMBL11137213 | 0.68 | ADRA2C (0.51) | IDO1ADRA2CMAPTCYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7858825-B2 | Acid and base stable diphenylmethanol derivatives and methods of use | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2010-12-28 | — | — | US | disclosed |
| US-20080200719-A1 | Acid and base stable diphenylmethanol derivatives and methods of use | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200719-A1 | Acid and base stable diphenylmethanol derivatives and methods of use | DPYD, DHODH, DAO | IDO1 1149/4885CYP24A1 1645/4885ADRA2C 4141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.