Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3785779 | 0.84 | MAPT (0.43) | MAPTRAB9AMDM2S1PR1S1PR3 | |
| SCHEMBL13018229 | 0.84 | MAPT (0.43) | MAPTRAB9AMDM2S1PR1S1PR3 | |
| SCHEMBL13018236 | 0.81 | MAPT (0.43) | MAPTRAB9AMDM2S1PR1S1PR3 | |
| SCHEMBL3783970 | 0.80 | ABL1 (0.40) | MAPTRAB9AMDM2S1PR1S1PR3 | |
| SCHEMBL13018237 | 0.78 | GAA (0.39) | MAPTRAB9AMDM2S1PR1S1PR3 | |
| SCHEMBL16525942 | 0.75 | MGLL (0.38) | MAPTRAB9AS1PR1S1PR3MEN1 | |
| SCHEMBL3787689 | 0.75 | MAPT (0.43) | MAPTLMNAMEN1KMT2A | |
| SCHEMBL13018239 | 0.74 | IDO1 (0.44) | MAPTLMNAIDO1MEN1KMT2A | |
| SCHEMBL3781334 | 0.72 | LMNA (0.44) | MAPTRAB9AMDM2S1PR1S1PR3 | |
| SCHEMBL3788314 | 0.72 | TP53 (0.44) | MAPTRAB9AMDM2S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015027137-A1 | IMPROVED SYNTHESIS OF CAPURAMYCIN AND ITS ANALOGUES | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2015-02-26 | — | — | WO | disclosed |
| US-7858825-B2 | Acid and base stable diphenylmethanol derivatives and methods of use | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2010-12-28 | — | — | US | disclosed |
| US-20080200719-A1 | Acid and base stable diphenylmethanol derivatives and methods of use | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200719-A1 | Acid and base stable diphenylmethanol derivatives and methods of use | DPYD, DHODH, DAO | MAPT 1367/4885RAB9A 2848/4885MDM2 770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.