Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 6/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.42 |
| ▸ | PRNP | P04156 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL378787 | 0.94 | ALDH1A1 (0.51) | CYP1A2CYP2C19CYP2D6ALDH1A1KMT2A | |
| SCHEMBL32685095 | 0.87 | KMT2A (0.58) | CYP1A2CYP2C19ALDH1A1KMT2AMEN1 | |
| SCHEMBL18333403 | 0.87 | KMT2A (0.58) | CYP1A2CYP2C19ALDH1A1KMT2AMEN1 | |
| SCHEMBL28010903 | 0.86 | CYP1A2 (0.47) | CYP1A2CYP2C19CYP2D6ALDH1A1KMT2A | |
| SCHEMBL15882797 | 0.86 | PDGFRB (0.55) | CYP1A2CYP2C19CYP2D6ALDH1A1KMT2A | |
| SCHEMBL28010902 | 0.84 | TDP1 (0.47) | CYP1A2CYP2C19CYP2D6ALDH1A1KMT2A | |
| SCHEMBL15882772 | 0.82 | PDGFRB (0.49) | CYP1A2CYP2C19CYP2D6ALDH1A1KMT2A | |
| SCHEMBL34462112 | 0.81 | TDP1 (0.44) | CYP1A2CYP2C19CYP2D6ALDH1A1KMT2A | |
| SCHEMBL31482564 | 0.81 | TDP1 (0.44) | CYP1A2CYP2C19CYP2D6ALDH1A1KMT2A | |
| SCHEMBL30859625 | 0.81 | KMT2A (0.44) | CYP1A2CYP2C19CYP2D6ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408791-A1 | FOSFLUCONAZOLE DERIVATIVES, SYNTHESIS, AND USE IN LONG ACTING FORMULATIONS | SEPS Pharma N.V. (BE) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010105910-A1 | FOSFLUCONAZOLE DERIVATIVES, SYNTHESIS, AND USE IN LONG ACTING FORMULATIONS | SEPS PHARMA N.V. (BE) | 2010-09-23 | — | — | WO | disclosed |