Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5038000 | 0.84 | ALDH1A1 (0.49) | ALDH1A1MAPTTDP1RAB9ANPC1 | |
| SCHEMBL30640280 | 0.74 | SLC6A4 (0.48) | HSPB1ALDH1A1TDP1XDHMEN1 | |
| SCHEMBL28489114 | 0.74 | SLC6A4 (0.48) | HSPB1ALDH1A1TDP1XDHMEN1 | |
| SCHEMBL21708340 | 0.73 | HTR7 (0.48) | HSPB1ALDH1A1MAPTGAATDP1 | |
| SCHEMBL31009349 | 0.73 | HSPB1 (0.62) | HSPB1ALDH1A1MAPTGAATDP1 | |
| SCHEMBL9312797 | 0.73 | ALDH1A1 (0.56) | ALDH1A1MAPTGAATDP1RAB9A | |
| SCHEMBL99419 | 0.73 | ALDH1A1 (0.57) | ALDH1A1MAPTTDP1RAB9ANPC1 | |
| SCHEMBL11452569 | 0.72 | ALDH1A1 (0.59) | ALDH1A1MAPTTDP1RAB9ANPC1 | |
| SCHEMBL7803368 | 0.71 | TDP1 (0.62) | ALDH1A1TDP1RAB9ANPC1CASP3 | |
| SCHEMBL7544094 | 0.71 | IKBKB (0.58) | ALDH1A1TDP1CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222638-A2 | BIARYL PDE4 INHIBITORS FOR TREATING INFLAMMATION | Decode Genetics EHF (IS) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009067600-A2 | BIARYL PDE4 INHIBITORS FOR TREATING INFLAMMATION | DECODE GENETICS EHF (IS) | 2009-05-28 | — | — | WO | disclosed |