Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.64 |
| ▸ | MAOA | P21397 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.62 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.62 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.62 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.47 |
| ▸ | AXL | P30530 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31716352 | 0.98 | TAAR1 (0.61) | TAAR1MAOACYP3A4CYP19A1CYP17A1 | |
| SCHEMBL2134718 | 0.96 | MAOA (0.62) | TAAR1MAOACYP3A4CYP19A1CYP17A1 | |
| SCHEMBL3790473 | 0.87 | MAOA (0.58) | TAAR1MAOACYP3A4CYP19A1CYP17A1 | |
| SCHEMBL17350172 | 0.87 | CYP3A4 (0.79) | TAAR1MAOACYP3A4CYP19A1CYP17A1 | |
| SCHEMBL30661714 | 0.87 | MAOA (0.58) | TAAR1MAOACYP3A4CYP19A1CYP17A1 | |
| SCHEMBL29394565 | 0.86 | MAOA (0.84) | TAAR1MAOACYP3A4CYP19A1CYP17A1 | |
| SCHEMBL29561461 | 0.86 | MAOA (0.84) | TAAR1MAOACYP3A4CYP19A1CYP17A1 | |
| SCHEMBL31131353 | 0.86 | MAOA (0.84) | TAAR1MAOACYP3A4CYP19A1CYP17A1 | |
| SCHEMBL311194 | 0.86 | MAOA (0.84) | TAAR1MAOACYP3A4CYP19A1CYP17A1 | |
| SCHEMBL19446666 | 0.86 | MAOA (0.84) | TAAR1MAOACYP3A4CYP19A1CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| WO-2009006315-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS FOR TREATING CYSTIC FIBROSIS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2009-01-08 | — | — | WO | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | TAAR1 1746/4885MAOA 348/4885CYP3A4 177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.