Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 13/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13257875 | 0.89 | EPHX2 (0.38) | RIPK1EPHX2ROCK2ROCK1DDR1 | |
| SCHEMBL3798917 | 0.85 | EPHX2 (0.39) | RIPK1EPHX2ROCK2ROCK1DDR1 | |
| SCHEMBL3788283 | 0.85 | EPHX2 (0.49) | RIPK1EPHX2ROCK2ROCK1DDR1 | |
| SCHEMBL3788739 | 0.80 | DDR1 (0.37) | DDR1 | |
| SCHEMBL3790192 | 0.80 | SCN5A (0.43) | RIPK1EPHX2ROCK2ROCK1SCN5A | |
| SCHEMBL3788832 | 0.78 | EPHX2 (0.40) | RIPK1EPHX2ROCK2ROCK1DDR1 | |
| SCHEMBL3790712 | 0.76 | EPHX2 (0.51) | RIPK1EPHX2ROCK2ROCK1DDR1 | |
| SCHEMBL3788935 | 0.75 | EPHX2 (0.47) | RIPK1EPHX2ROCK2ROCK1 | |
| SCHEMBL3805799 | 0.75 | DDR1 (0.41) | EPHX2DDR1 | |
| SCHEMBL3787175 | 0.74 | EPHX2 (0.57) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010096722-A1 | 3-OXO-2, 3-DIHYDRO- [1,2, 4] TRIAZOLO [4, 3-A]PYRIDINES AS SOLUBLE EPOXIDE HYDROLASE (SEH) INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-26 | — | — | WO | disclosed |
| WO-2010096722-A1 | 3-OXO-2, 3-DIHYDRO- [1,2, 4] TRIAZOLO [4, 3-A]PYRIDINES AS SOLUBLE EPOXIDE HYDROLASE (SEH) INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-26 | — | — | WO | disclosed |