Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13258587 | 0.89 | EPHX2 (0.60) | EPHX2PPARG | |
| SCHEMBL3805799 | 0.87 | DDR1 (0.41) | EPHX2PPARG | |
| SCHEMBL3788283 | 0.79 | EPHX2 (0.49) | EPHX2 | |
| SCHEMBL13257875 | 0.79 | EPHX2 (0.38) | EPHX2 | |
| SCHEMBL3798917 | 0.79 | EPHX2 (0.39) | EPHX2 | |
| SCHEMBL3788290 | 0.78 | EPHX2 (0.46) | EPHX2 | |
| SCHEMBL3788746 | 0.75 | EPHX2 (0.45) | EPHX2 | |
| SCHEMBL20589559 | 0.75 | EPHX2 (1.00) | EPHX2PPARG | |
| SCHEMBL3788876 | 0.74 | RIPK1 (0.38) | EPHX2 | |
| SCHEMBL3794448 | 0.74 | EPHX2 (0.44) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010096722-A1 | 3-OXO-2, 3-DIHYDRO- [1,2, 4] TRIAZOLO [4, 3-A]PYRIDINES AS SOLUBLE EPOXIDE HYDROLASE (SEH) INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-26 | — | — | WO | disclosed |