Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11524369 | 0.78 | KMT2A (0.59) | MAPTNPC1RAB9AHTTPOLB | |
| SCHEMBL11526361 | 0.77 | HTT (0.52) | MAPTNPC1RAB9AHTTPOLB | |
| SCHEMBL9547503 | 0.77 | RAB9A (0.89) | MAPTNPC1RAB9AKDM4EHTT | |
| SCHEMBL3796561 | 0.76 | EPHX2 (0.58) | MAPTNPC1RAB9AHTTMEN1 | |
| SCHEMBL3789018 | 0.72 | EPHX2 (0.57) | MAPTNPC1RAB9AHTTMEN1 | |
| SCHEMBL11049543 | 0.72 | MAPT (1.00) | MAPTNPC1RAB9AHTTPOLB | |
| SCHEMBL30697002 | 0.72 | MAPT (1.00) | MAPTNPC1RAB9AHTTPOLB | |
| SCHEMBL14470506 | 0.71 | IMPDH2 (0.73) | MAPTNPC1RAB9AKDM4ECA2 | |
| SCHEMBL8325083 | 0.71 | RAB9A (0.71) | MAPTNPC1RAB9AKDM4EPOLB | |
| SCHEMBL8596702 | 0.71 | RAB9A (0.71) | MAPTNPC1RAB9AKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4168260-A | PROTECTION AGAINST DEGRADATION BY HEAT OR LIGHT | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-09-18 | — | — | US | disclosed |