Styrene

Styrene

SCHEMBL3789273

C=CC#N.C=CC#N.C=CC(=O)O.C=Cc1ccccc1.C=Cc1ccccc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.54
TSHR P16473 2/20 0.54
AKT1 P31749 1/20 0.41
HDAC3 O15379 1/20 0.41
TNKS O95271 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HCAR2 Q8TDS4 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
TNKS2 Q9H2K2 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
HDAC9 Q9UKV0 1/20 0.41
HDAC5 Q9UQL6 1/20 0.41
MCL1 Q07820 2/20 0.41
LMNA P02545 3/20 0.39
TGM2 P21980 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL27670716 1.00 ALDH1A1 (0.54) ALDH1A1TSHRAKT1HDAC3TNKS
Styrene SCHEMBL123961 1.00 ALDH1A1 (0.54) ALDH1A1TSHRAKT1HDAC3TNKS
Styrene SCHEMBL23825515 0.98 ALDH1A1 (0.52) ALDH1A1TSHRAKT1HDAC3TNKS
Styrene SCHEMBL27190847 0.98 ALDH1A1 (0.52) ALDH1A1TSHRAKT1HDAC3TNKS
Styrene SCHEMBL341005 0.96 ALDH1A1 (0.50) ALDH1A1TSHRAKT1HDAC3TNKS
Styrene SCHEMBL4375720 0.92 ALDH1A1 (0.58) ALDH1A1TSHRAKT1HDAC3TNKS
Styrene SCHEMBL28191189 0.91 ALDH1A1 (0.52) ALDH1A1TSHRAKT1HDAC3TNKS
Styrene SCHEMBL4372746 0.89 ALDH1A1 (0.50) ALDH1A1TSHRAKT1HDAC3TNKS
Styrene SCHEMBL157052 0.89 ALDH1A1 (0.54) ALDH1A1TSHRAKT1HDAC3TNKS
Styrene SCHEMBL1980399 0.89 ALDH1A1 (0.54) ALDH1A1TSHRAKT1HDAC3TNKS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010056452-A2 DIMERIC CYANOACRYLATE COMPOUNDS AS RED-SHIFTED UV ABSORBERS CYTEC TECHNOLOGY CORP. (US) 2010-05-20 WO claimed
WO-2010056452-A2 DIMERIC CYANOACRYLATE COMPOUNDS AS RED-SHIFTED UV ABSORBERS CYTEC TECHNOLOGY CORP. (US) 2010-05-20 WO disclosed