Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21727707 | 0.84 | S1PR1 (0.41) | ALDH1A1TSHRMAPK1TDP1S1PR1 | |
| SCHEMBL10062458 | 0.84 | S1PR1 (0.41) | ALDH1A1TSHRMAPK1TDP1S1PR1 | |
| SCHEMBL346399 | 0.83 | ALDH1A1 (0.53) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL44501 | 0.83 | ALDH1A1 (0.67) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| Hydrochloric Acid SCHEMBL2864667 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| Hydrochloric Acid SCHEMBL2870922 | 0.81 | ALDH1A1 (0.64) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL13821789 | 0.77 | ALDH1A1 (0.81) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL1623876 | 0.77 | ALDH1A1 (0.58) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL12190212 | 0.77 | S1PR1 (0.50) | ALDH1A1MAPK1S1PR1NPC1RAB9A | |
| SCHEMBL29441542 | 0.74 | TRPA1 (0.48) | ALDH1A1MAPK1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2554155-B1 | ONE-PACK DENTAL ADHESIVE MATERIAL COMPOSITION | KURARAY NORITAKE DENTAL INC (JP) | 2020-08-05 | — | — | EP | disclosed |
| EP-2409997-B1 | REDOX-CURING TYPE COMPOSITION | KURARAY NORITAKE DENTAL INC (JP) | 2016-11-16 | — | — | EP | disclosed |
| EP-2554155-A1 | ONE-PACK DENTAL ADHESIVE MATERIAL COMPOSITION | KURARAY NORITAKE DENTAL INC. (JP) | 2013-02-06 | — | — | EP | disclosed |
| EP-2409997-A1 | REDOX-CURING TYPE COMPOSITION | Kuraray Medical Inc. (JP) | 2012-01-25 | — | — | EP | disclosed |