SCHEMBL346399

SCHEMBL346399

Cc1ccc(N(C)C)cc1C

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.53
TSHR P16473 5/20 0.53
ALOX15 P16050 2/20 0.53
HSD17B10 Q99714 1/20 0.53
MAPT P10636 3/20 0.52
APP P05067 2/20 0.46
TERT O14746 1/20 0.46
APAF1 O14727 1/20 0.42
SLC2A1 P11166 1/20 0.42
CYP3A4 P08684 2/20 0.42
MAPK1 P28482 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
TP53 P04637 1/20 0.42
CRHR1 P34998 1/20 0.42
KDM4E B2RXH2 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2864667 0.97 ALDH1A1 (0.50) ALDH1A1TSHRALOX15HSD17B10MAPT
SCHEMBL13569447 0.83 ALDH1A1 (0.42) ALDH1A1TSHRALOX15HSD17B10MAPT
SCHEMBL378937 0.83 ALDH1A1 (0.48) ALDH1A1TSHRALOX15HSD17B10MAPT
SCHEMBL13990194 0.81 ALDH1A1 (0.50) ALDH1A1TSHRALOX15HSD17B10MAPT
SCHEMBL30966777 0.81 ALDH1A1 (0.50) ALDH1A1TSHRALOX15HSD17B10MAPT
SCHEMBL10304751 0.80 ALDH1A1 (0.50) ALDH1A1TSHRALOX15HSD17B10MAPT
SCHEMBL7763414 0.80 ALDH1A1 (0.43) ALDH1A1TSHRALOX15HSD17B10MAPT
SCHEMBL28913745 0.79 ALDH1A1 (0.44) ALDH1A1TSHRALOX15HSD17B10MAPT
SCHEMBL516025 0.79 ALDH1A1 (0.48) ALDH1A1TSHRALOX15HSD17B10MAPT
SCHEMBL3459335 0.79 ALDH1A1 (0.48) ALDH1A1TSHRALOX15HSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 751 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102821737-B Dental adhesive material kit KURARAY NORITAKE DENTAL INC 2015-01-14 CN claimed
US-4215209-A ACRYLATE ESTER MONOMER, FREE RADICAL INHIBITOR, CHELATOR AND A SULFONAMIDE OR TERT-AMINE ACCELERATOR NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1980-07-29 US claimed
US-20260144714-A1 KIT FOR PREPARING CURABLE COMPOSITION FOR DENTAL MATERIAL, CURABLE COMPOSITION FOR DENTAL MATERIAL, AND DENTAL MATERIAL MITSUI CHEMICALS, INC. (JP) 2026-05-28 US disclosed
US-12622847-B2 Organosilicon compound and dental composition containing same KURARAY NORITAKE DENTAL INC. (JP) 2026-05-12 US disclosed
US-20260124121-A1 POLYMERIZABLE DENTAL COMPOSITION TROETSCHLER TOBIAS (DE) 2026-05-07 US disclosed
EP-3861977-B1 (METH)ACRYLATE, MONOMER COMPOSITION, MOLDED BODY, COMPOSITION FOR DENTAL MATERIAL, AND DENTAL MATERIAL MITSUI CHEMICALS INC (JP) 2026-05-06 EP disclosed
EP-4736833-A1 POLYMERIZABLE DENTAL COMPOSITION DENTSPLY SIRONA Inc. (US) 2026-05-06 EP disclosed
EP-4725470-A1 CURABLE DENTAL COMPOSITION Kuraray Noritake Dental Inc. (JP) 2026-04-15 EP disclosed
US-12564543-B2 Dental composition KURARAY NORITAKE DENTAL INC. (JP) 2026-03-03 US disclosed
US-12527725-B2 Solvent-free dental adhesive composition KURARAY NORITAKE DENTAL INC. (JP) 2026-01-20 US disclosed
US-12478562-B2 Dental restoration material composition KURARAY NORITAKE DENTAL INC. (JP) 2025-11-25 US disclosed
EP-0980682-A1 Bonding compositions for dental use KURARAY CO., LTD. (JP) 2000-02-23 EP disclosed
EP-0948955-A1 POLYMERIZABLE DENTAL COMPOSITION KURARAY CO., LTD. (JP) 1999-10-13 EP disclosed
EP-0942006-A2 Catalyst for olefin polymer production and process for olefin polymer production employing the catalyst TOSOH CORPORATION (JP) 1999-09-15 EP disclosed
EP-0849292-A1 Olefin polymerisation catalysts and processes for producing olefin polymers TOSOH CORPORATION (JP) 1998-06-24 EP disclosed
EP-0073890-B1 AN ANAEROBIC COMPOSITION, A REACTIVE THICKENER CONTAINED THEREIN AND USE OF THE COMPOSITION AS ADHESIVE OR SEALANT National Starch and Chemical Corporation (US) 1986-04-02 EP disclosed
EP-0017151-B1 COLD CURING MATERIALS FOR DENTAL PURPOSES WITH POLYMERISATION-ACTIVE SULFONES BAYER AG (DE) 1984-02-15 EP disclosed
US-4401793-A Polymeric adducts with pendant polymerizable double bonds, their preparation and use as reactive thickeners in improved anaerobic compositions NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1983-08-30 US disclosed
EP-0073890-A1 An anaerobic composition, a reactive thickener contained therein and use of the composition as adhesive or sealant National Starch and Chemical Corporation (US) 1983-03-16 EP disclosed
US-4215209-A ACRYLATE ESTER MONOMER, FREE RADICAL INHIBITOR, CHELATOR AND A SULFONAMIDE OR TERT-AMINE ACCELERATOR NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1980-07-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12527725-B2 Solvent-free dental adhesive composition CDH1, ITGA1, ITGB8 ALDH1A1 1885/4885TSHR 3896/4885ALOX15 153/4885
US-20260144714-A1 KIT FOR PREPARING CURABLE COMPOSITION FOR DENTAL MATERIAL, CURABLE COMPOSITION FOR DENTAL MATERIAL, AND DENTAL MATERIAL CAD, KIT, ILK ALDH1A1 675/4885TSHR 4509/4885ALOX15 1851/4885
US-12564543-B2 Dental composition CAD, ARCN1, MAT1A ALDH1A1 306/4885TSHR 4074/4885ALOX15 1864/4885
US-12478562-B2 Dental restoration material composition CAD, MAT2B, RER1 ALDH1A1 209/4885TSHR 3780/4885ALOX15 549/4885
US-12622847-B2 Organosilicon compound and dental composition containing same MSL1, ITGA1, ITGAL ALDH1A1 668/4885TSHR 4185/4885ALOX15 2690/4885
US-20260124121-A1 POLYMERIZABLE DENTAL COMPOSITION F12, RAD51, PFN1 ALDH1A1 706/4885TSHR 2717/4885ALOX15 2215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.