Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3789275 | 0.90 | GAA (0.53) | GAAALDH1A1HTTSMN1; SMN2POLB | |
| SCHEMBL3788115 | 0.90 | ALDH1A1 (0.62) | GAAALDH1A1HTTSMN1; SMN2POLB | |
| SCHEMBL3781736 | 0.89 | GAA (0.51) | GAAALDH1A1HTTSMN1; SMN2POLB | |
| SCHEMBL3784624 | 0.89 | ALDH1A1 (0.59) | GAAALDH1A1HTTSMN1; SMN2POLB | |
| SCHEMBL3786746 | 0.85 | GAA (0.65) | GAAALDH1A1HTTSMN1; SMN2POLB | |
| SCHEMBL3790147 | 0.84 | GAA (0.60) | GAAALDH1A1HTTSMN1; SMN2POLB | |
| SCHEMBL3786389 | 0.84 | ALDH1A1 (0.59) | GAAALDH1A1HTTSMN1; SMN2POLB | |
| SCHEMBL27825330 | 0.81 | POLB (0.70) | GAAALDH1A1HTTSMN1; SMN2POLB | |
| SCHEMBL3786248 | 0.80 | GAA (0.53) | GAAALDH1A1HTTSMN1; SMN2POLB | |
| SCHEMBL3786296 | 0.80 | ALDH1A1 (0.51) | GAAALDH1A1HTTSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | GAA 1755/4885ALDH1A1 4339/4885HTT 3090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.