Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.47 |
| ▸ | METAP2 | P50579 | 3/20 | 0.44 |
| ▸ | METAP1 | P53582 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | SLC40A1 | Q9NP59 | 8/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL249779 | 0.80 | METAP2 (0.64) | PDE4APDE4CPDE4DMETAP2METAP1 | |
| SCHEMBL6638222 | 0.80 | TRPA1 (0.43) | PDE4APDE4CPDE4DKDM4ETSHR | |
| SCHEMBL29937434 | 0.80 | TRPA1 (0.43) | PDE4APDE4CPDE4DKDM4ETSHR | |
| SCHEMBL3380041 | 0.79 | PDE4A (0.38) | PDE4APDE4CPDE4DSLC40A1CA1 | |
| SCHEMBL7608263 | 0.78 | PDE4A (0.40) | PDE4APDE4CPDE4DMETAP2METAP1 | |
| SCHEMBL27854709 | 0.77 | CCR1 (0.47) | PDE4APDE4CPDE4DMETAP2METAP1 | |
| SCHEMBL21260401 | 0.76 | PDE4A (0.39) | PDE4APDE4CPDE4D | |
| SCHEMBL4149669 | 0.75 | PDE4A (0.50) | PDE4APDE4CPDE4DMETAP2METAP1 | |
| SCHEMBL18318080 | 0.75 | PDE4A (0.45) | PDE4APDE4CPDE4DMETAP2METAP1 | |
| SCHEMBL12578335 | 0.75 | METAP2 (0.51) | PDE4APDE4CPDE4DMETAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010112826-A2 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2010-10-07 | — | — | WO | disclosed |