Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD5 | P21918 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18319625 | 0.90 | SLC40A1 (0.43) | PDE4APDE4CPDE4DMETAP2METAP1 | |
| SCHEMBL27875839 | 0.84 | KDM4E (0.38) | PDE4APDE4CPDE4DDRD2ALDH1A1 | |
| SCHEMBL315126 | 0.83 | PDE4A (0.40) | PDE4APDE4CPDE4DMETAP2METAP1 | |
| SCHEMBL1347229 | 0.81 | KDM1A (0.39) | PDE4APDE4CPDE4DMETAP2METAP1 | |
| SCHEMBL21260401 | 0.81 | PDE4A (0.39) | PDE4APDE4CPDE4DTRPV4SLC22A12 | |
| SCHEMBL16116265 | 0.80 | DRD2 (0.35) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL31505101 | 0.79 | PDE4A (0.38) | PDE4APDE4CPDE4DMETAP2METAP1 | |
| SCHEMBL22121960 | 0.79 | PDE4A (0.40) | PDE4APDE4CPDE4DMETAP2METAP1 | |
| SCHEMBL249779 | 0.79 | METAP2 (0.64) | PDE4APDE4CPDE4DMETAP2METAP1 | |
| SCHEMBL3878750 | 0.79 | NAPRT (0.49) | PDE4APDE4CPDE4DALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0947508-B1 | Process for recovery of pyridine-2,3-dicarboxylic acid | DSM NV (NL) | 2002-08-07 | — | — | EP | disclosed |
| US-6133450-A | PROCESS STREAM SUBJECTED TO NANOFILTRATION AT PH HIGHER THAN 4.5 WHEREIN IN SAID NANOFILTRATION FEED PRESSURE IS HIGHER THAN ATMOSPHERIC PRESSURE, AND PYRIDINE-2,3-DICARBOXYLIC ACID CONCENTRATE IS UTILIZED | DSM N.V. (NL) | 2000-10-17 | — | — | US | disclosed |
| EP-0947508-A1 | Process for recovery of pyridine-2,3-dicarboxylic acid | DSM N.V. (NL) | 1999-10-06 | — | — | EP | disclosed |