Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 7/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.37 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.37 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.37 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3789422 | 0.83 | ELANE (0.50) | HPGDELANEALDH1A1RAB9ALMNA | |
| SCHEMBL14313368 | 0.74 | MAPT (0.41) | CYP1A2CYP2C19ALDH1A1MAPT | |
| SCHEMBL9360017 | 0.71 | CYP1A2 (0.69) | CYP1A2CYP2D6HPGDCYP2C19PTGS1 | |
| SCHEMBL11967001 | 0.70 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL11108746 | 0.70 | ELANE (0.59) | CYP1A2CYP2D6HPGDCYP2C19ELANE | |
| SCHEMBL14723237 | 0.68 | ELANE (0.58) | HPGDELANEALDH1A1RAB9ALMNA | |
| SCHEMBL11966982 | 0.68 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL27949094 | 0.68 | TSHR (0.48) | CYP1A2CYP2C19PTGS1PTGS2ALDH1A1 | |
| SCHEMBL9879563 | 0.67 | SRD5A2 (0.54) | CYP1A2CYP2D6HPGDCYP2C19ELANE | |
| SCHEMBL4194206 | 0.67 | HPGD (0.54) | CYP1A2CYP2D6HPGDCYP2C19ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1371694-B1 | Polymeric nanoparticle formulations and their use for improving the dirt pick up resistance of a coating | ROHM & HAAS (US) | 2010-03-03 | — | — | EP | claimed |