Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3792639 | 1.00 | EPHX2 (0.35) | EPHX2MEN1THRBHTTKMT2A | |
| SCHEMBL10179363 | 1.00 | EPHX2 (0.35) | EPHX2MEN1THRBHTTKMT2A | |
| SCHEMBL3799551 | 1.00 | EPHX2 (0.35) | EPHX2MEN1THRBHTTKMT2A | |
| SCHEMBL3848643 | 1.00 | EPHX2 (0.35) | EPHX2MEN1THRBHTTKMT2A | |
| SCHEMBL20913246 | 1.00 | EPHX2 (0.35) | EPHX2MEN1THRBHTTKMT2A | |
| SCHEMBL19319568 | 0.91 | CA2 (0.31) | EPHX2CA2 | |
| SCHEMBL19319569 | 0.91 | CA2 (0.31) | EPHX2CA2 | |
| SCHEMBL5379141 | 0.91 | CA2 (0.31) | EPHX2CA2 | |
| SCHEMBL16546063 | 0.91 | CA2 (0.31) | EPHX2CA2 | |
| SCHEMBL19319570 | 0.91 | CA2 (0.31) | EPHX2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1607743-B1 | Silane molecules with pre-activated and protein-resistant functionalities and silane films comprising such molecules | IMEC (BE) | 2010-08-11 | — | — | EP | disclosed |
| US-7285674-B2 | Silane molecules with pre-activated and protein-resistant functionalities and silane films comprising such molecules | INTERUNIVERSITAIR MICROELEKTRONICA CENTRUM (IMEC) (BE) | 2007-10-23 | — | — | US | disclosed |
| EP-1607743-A1 | Silane molecules with pre-activated and protein-resistant functionalities and silane films comprising such molecules | INTERUNIVERSITAIR MICROELEKTRONICA CENTRUM ( IMEC) (BE) | 2005-12-21 | — | — | EP | disclosed |
| US-20050255514-A1 | Silane molecules with pre-activated and protein-resistant functionalities and silane films comprising such molecules | INTERUNIVERSITAIR MICROELEKTRONICA CENTRUM (IMEC) (BE) | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050255514-A1 | Silane molecules with pre-activated and protein-resistant functionalities and silane films comprising such molecules | YWHAH, YWHAE, YWHAB | EPHX2 4730/4885MEN1 3343/4885THRB 672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.