Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 4/20 | 0.54 |
| ▸ | CFD | P00746 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | GAPDH | P04406 | 2/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3782026 | 0.90 | BACE1 (0.55) | BACE1CFDCYP19A1TNFSF11ALDH1A1 | |
| SCHEMBL3783939 | 0.86 | BACE1 (0.54) | BACE1CFDCYP19A1TNFSF11ALDH1A1 | |
| SCHEMBL27788206 | 0.85 | BACE1 (0.40) | BACE1CYP19A1ALDH1A1PTGDR2TUBB4A | |
| SCHEMBL3784462 | 0.85 | BACE1 (0.43) | BACE1TNFSF11ALDH1A1GAPDHPTGDR2 | |
| SCHEMBL3790378 | 0.83 | NCOA1 (0.49) | BACE1CFDALDH1A1KDM4EGAA | |
| SCHEMBL3791104 | 0.80 | ALDH1A1 (0.39) | BACE1CYP19A1ALDH1A1PTGDR2GAA | |
| SCHEMBL6247630 | 0.80 | TSHR (0.58) | CFDCYP19A1TNFSF11ALDH1A1NR3C1 | |
| SCHEMBL3784825 | 0.79 | ALDH1A1 (0.41) | BACE1CYP19A1TNFSF11ALDH1A1NR3C1 | |
| SCHEMBL27788175 | 0.79 | PTGDR2 (0.36) | BACE1CYP19A1ALDH1A1PTGDR2GAA | |
| SCHEMBL3245649 | 0.78 | PIM1 (0.47) | CFDCYP19A1ALDH1A1NR3C1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112898168-A | Salt of 2-hydroxybenzylamine-succinic acid and preparation method thereof | 天津大学 | 2021-06-04 | — | — | CN | disclosed |
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | BACE1 925/4885CFD 3738/4885CYP19A1 176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.