Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | TK1 | P04183 | 2/20 | 0.59 |
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8424933 | 0.93 | POLB (0.61) | POLBTK1BCHE | |
| SCHEMBL8586579 | 0.90 | BCHE (0.59) | TYMSPOLBTK1BCHE | |
| SCHEMBL2543582 | 0.89 | TYMS (0.63) | TYMSPOLBTK1BCHE | |
| SCHEMBL887852 | 0.86 | TK1 (0.69) | TYMSPOLBTK1BCHE | |
| SCHEMBL16359946 | 0.86 | TK1 (0.69) | TYMSPOLBTK1BCHE | |
| SCHEMBL24548457 | 0.86 | POLB (0.66) | TYMSPOLBTK1BCHE | |
| SCHEMBL17232081 | 0.85 | TK1 (0.69) | TYMSPOLBTK1BCHE | |
| SCHEMBL4809523 | 0.85 | POLB (0.68) | TYMSPOLBTK1BCHE | |
| SCHEMBL22943603 | 0.85 | TK1 (0.69) | TYMSPOLBTK1BCHE | |
| SCHEMBL12918450 | 0.85 | TK1 (0.69) | TYMSPOLBTK1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7741294-B1 | Non-standard nucleobases implementing the isocytidine and isoguanosine hydrogen bonding patterns | BENNER STEVEN ALBERT | 2010-06-22 | — | — | US | disclosed |