Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | TK1 | P04183 | 2/20 | 0.61 |
| ▸ | BCHE | P06276 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3789657 | 0.93 | TYMS (0.63) | POLBTK1BCHE | |
| SCHEMBL8586579 | 0.91 | BCHE (0.59) | POLBTK1BCHE | |
| SCHEMBL4194754 | 0.90 | POLB (0.55) | POLBTK1BCHE | |
| SCHEMBL8744206 | 0.87 | POLB (0.57) | POLBTK1BCHE | |
| SCHEMBL2543582 | 0.86 | TYMS (0.63) | POLBTK1BCHE | |
| SCHEMBL8655467 | 0.86 | TYMS (0.66) | POLBTK1BCHE | |
| SCHEMBL8527785 | 0.86 | TK1 (0.64) | POLBTK1BCHE | |
| SCHEMBL9550743 | 0.86 | TK1 (0.64) | POLBTK1BCHE | |
| SCHEMBL8424931 | 0.86 | POLB (0.67) | POLBTK1 | |
| SCHEMBL4731694 | 0.85 | RNASE1 (0.67) | POLBTK1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962291-A | MONOCLONAL ANTIBODY CAPABLE OF HYDROLYZING A SUBSTRATE; HAS TWO BINDING SITES: ONE FOR FREE METAL ION, ONE FOR SUBSTRATE | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 1999-10-05 | — | — | US | disclosed |