Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TK1 | P04183 | 2/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3789657 | 0.89 | TYMS (0.63) | TYMSPOLBTK1BCHE | |
| SCHEMBL6047006 | 0.89 | TYMS (0.58) | TYMSPOLBBCHE | |
| SCHEMBL6047004 | 0.89 | TYMS (0.58) | TYMSPOLBBCHE | |
| SCHEMBL9947618 | 0.87 | TYMS (0.61) | TYMSPOLBTK1BCHE | |
| SCHEMBL3063249 | 0.87 | TYMS (0.68) | TYMSPOLBTK1 | |
| SCHEMBL8428624 | 0.87 | TYMS (0.68) | TYMSPOLBTK1 | |
| SCHEMBL548542 | 0.87 | TYMS (0.54) | TYMSPOLBTK1 | |
| SCHEMBL7040500 | 0.86 | TYMS (0.60) | TYMSPOLBTK1 | |
| SCHEMBL7038116 | 0.86 | TYMS (0.60) | TYMSPOLBTK1 | |
| SCHEMBL8424933 | 0.86 | POLB (0.61) | POLBTK1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3206723-A1 | BIOLOGICAL INDICATOR | American Sterilizer Company (US) | 2017-08-23 | — | — | EP | claimed |
| US-9701968-B2 | Biological indicator | AMERICAN STERILIZER COMPANY (US) | 2017-07-11 | — | — | US | claimed |
| US-20160312263-A1 | BIOLOGICAL INDICATOR | AMERICAN STERILIZER CO (US) | 2016-10-27 | — | — | US | claimed |
| WO-2016060714-A1 | BIOLOGICAL INDICATOR | AMERICAN STERILIZER COMPANY (US) | 2016-04-21 | — | — | WO | claimed |
| US-20160102335-A1 | BIOLOGICAL INDICATOR | AMERICAN STERILIZER COMPANY | 2016-04-14 | — | — | US | claimed |
| US-8507248-B2 | Genetically engineered biological indicator | AMERICAN STERILIZER COMPANY (US) | 2013-08-13 | — | — | US | claimed |
| US-8173389-B2 | Process for determining the effectiveness of a sterilization | AMERICAN STERILIZER COMPANY (US) | 2012-05-08 | — | — | US | claimed |
| US-20090117603-A1 | STERILIZATION INDICATOR | FRANCISKOVICH PHILLIP P | 2009-05-07 | — | — | US | claimed |
| US-20080070231-A1 | Reporter genes taken up by microorganism, and repressor gene inhibits expression | AMERICAN STERILIZER COMPANY | 2008-03-20 | — | — | US | claimed |
| US-20080070272-A1 | STERILIZATION INDICATOR | AMERICAN STERILIZER COMPANY | 2008-03-20 | — | — | US | claimed |
| WO-2023076866-A1 | TRICYCLIC SULFOXIMINE INHIBITORS OF ENPP1 | VOLASTRA THERAPEUTICS, INC. (US) | 2023-05-04 | — | — | WO | disclosed |
| CN-115996912-A | Iminothiolanone inhibitors of ENPP1 | 沃拉斯查疗法公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-114728971-A | 2-amino-S6-substituted thiopurine compounds as inhibitors of ENPP1 protein | 阿托恩波罗斯生命科学私人有限公司 | 2022-07-08 | — | — | CN | disclosed |
| EP-3911153-A1 | TREATMENT OF DISEASES INVOLVING DEFICIENCY OF ENPP1 OR ENPP3 | Inozyme Pharma, Inc. (US) | 2021-11-24 | — | — | EP | disclosed |
| WO-2020150716-A1 | TREATMENT OF DISEASES INVOLVING DEFICIENCY OF ENPP1 OR ENPP3 | INOZYME PHARMA, INC. (US) | 2020-07-23 | — | — | WO | disclosed |
| US-6623955-B2 | Exposing source of active enzyme to sterilization cycle, contacting enzyme after cycle with aqueous buffer and substrate specific for and reactive with active enzyme to form enzyme modified product, detecting viable microorganisms | 3M INNOVATIVE PROPERTIES COMPANY | 2003-09-23 | — | — | US | disclosed |
| US-20030157588-A1 | Exposing source of active enzyme to sterilization cycle, contacting enzyme after cycle with aqueous buffer and substrate specific for and reactive with active enzyme to form enzyme modified product, detecting viable microorganisms | 3M INNOVATIVE PROPERTIES COMPANY | 2003-08-21 | — | — | US | disclosed |
| WO-2003040340-A2 | NUCLEIC ACID AND CORRESPONDING PROTEIN ENTITLED 161P2F10B USEFUL IN TREATMENT AND DETECTION OF CANCER | AGENSYS, INC. (US) | 2003-05-15 | — | — | WO | disclosed |
| US-20030077688-A1 | Rapid read-out biological indicator | MINNESOTA MINING AND MANUFACTURING COMPANY TO 3M INNOVATIVE PROPERTIES COMPANY | 2003-04-24 | — | — | US | disclosed |
| EP-0371682-A2 | Rapid method for determining efficacy of a sterilization cycle and rapid read-out biological indicator | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-06-06 | — | — | EP | disclosed |